Deep learning analysis of the myocardium in coronary CT angiography for identification of patients with functionally significant coronary artery stenosis [PDF]
, 2017 In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in clinical ...
Išgum, Ivana +7 more
core +14 more sources
Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI [PDF]
, 2017 BACKGROUND: Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone.
Al-Lamee, R +6 more
core +4 more sources
Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments [PDF]
, 2015 Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and improvements in the diagnosis and treatment of CAD can reduce the health and economic burden of this condition.
Berry, Colin +5 more
core +1 more source
Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial [PDF]
, 2013 <p>Background: In patients with acute non–ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective.
Balachandran, Kanarath P. +10 more
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Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution [PDF]
, 2017 In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be ...
Berry, Colin +2 more
core +1 more source
A New Approach in Risk Stratification by Coronary CT Angiography. [PDF]
, 2014 For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks.
Budoff, Matthew J, Nakanishi, Rine
core +3 more sources
Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve [PDF]
, 2017 Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine.
Berry, Colin +10 more
core +1 more source
Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization [PDF]
, 2016 Objectives: In the presence of a chronically occluded coronary artery, the collateral circulation matures by a process of arteriogenesis; however, there is considerable variation between individuals in the functional capacity of that collateral network ...
Alamgir, Farquad +6 more
core +1 more source
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]
, 2018 The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin +2 more
core +1 more source
Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization [PDF]
, 2016 Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel in ...
Alamgir, Farquad +5 more
core +1 more source