Real-Life Fractional Flow Reserve [PDF]
Article, see p 2241 Rare are the approaches that have changed our understanding of coronary artery disease as has fractional flow reserve (FFR). After extensive animal and human validation work and hypothesis-generating observational studies,1 larger randomized trials with a superiority design have reshaped our therapeutic strategies in stable ...
De Bruyne, Bernard +2 more
openaire +3 more sources
The use of coronary physiology in patients with chronic coronary syndromes is highly variable, and the evidence base complex. Tests of coronary physiology have traditionally been invasive (e.g., fractional flow reserve), but novel non-invasive methods ...
Alec Saunders, Nick Curzen
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Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution [PDF]
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be ...
Berry, Colin +2 more
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Functional assessment of a left coronary-pulmonary artery fistula by coronary flow reserve [PDF]
We report a 71-year-old man who presented with atypical chest pain. Coronary angiography did not reveal left main or proximal left anterior descending coronary artery stenosis, but a fistulous communication with a stronger tube-like fistula was present ...
Forster, Tamás +3 more
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Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve [PDF]
Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine.
Berry, Colin +10 more
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Invasive physiological indices to determine the functional significance of coronary stenosis
Physiological measurements are now commonly used to assess coronary lesions in the cardiac catheterisation laboratory, and this practice is evidence-based and supported by clinical guidelines. Fractional flow reserve is currently the gold standard method
Firas R. AL-Obaidi +2 more
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Safety of the Deferral of Coronary Revascularization on the Basis of Instantaneous Wave-Free Ratio and Fractional Flow Reserve Measurements in Stable Coronary Artery Disease and Acute Coronary Syndromes. [PDF]
OBJECTIVES: The aim of this study was to investigate the clinical outcomes of patients deferred from coronary revascularization on the basis of instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR) measurements in stable angina pectoris ...
Al-Lamee, R +11 more
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Effect of Varying Hemodynamic and Vascular Conditions on Fractional Flow Reserve: An In Vitro Study
BackgroundThe aim of this study was to investigate the impact of varying hemodynamic conditions on fractional flow reserve (ratio of pressure distal [Pd] and proximal [Pa] to stenosis under hyperemia) in an in vitro setting.
Kranthi K. Kolli +4 more
doaj +1 more source
The Multi-center Evaluation of the Accuracy of the Contrast MEdium INduced Pd/Pa RaTiO in Predicting FFR (MEMENTO-FFR) Study. [PDF]
AIMS: Adenosine administration is needed for the achievement of maximal hyperaemia fractional flow reserve (FFR) assessment. The objective was to test the accuracy of Pd/Pa ratio registered during submaximal hyperaemia induced by non-ionic contrast ...
Amabile, N +5 more
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Diagnostic performance of wireless fractional flow reserve: a meta-analysis
Introduction The aim of this study was to evaluate diagnostic performance of wireless fractional flow reserve (FFR) used in patients with coronary artery disease (CAD).
Wen Pan, Qing-Jun Liu
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