Results 41 to 50 of about 55,652 (297)

Improvement of Fractional Flow Reserve after Percutaneous Coronary Intervention Does Not Necessarily Indicate Increased Coronary Flow

European Cardiology Review, 2019
Coronary flow is expected to increase by epicardial lesion modification after successful percutaneous coronary intervention (PCI) in stable angina. According to the concept of fractional flow reserve (FFR), the improvement in FFR after PCI reflects the ...
Rikuta Hamaya, Yoshihisa Kanaji, Eisuke Usui, Masahiro Hoshino, Tadashi Murai, Taishi Yonetsu, Tsunekazu Kakuta   +6 more
doaj   +1 more source

Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial [PDF]

, 2013
<p>Background: In patients with acute non–ST-elevation myocardial infarction (NSTEMI), coronary arteriography is usually recommended; but visual interpretation of the angiogram is subjective.
Balachandran, Kanarath P., Berry, Colin, Briggs, Andrew H., Curzen, Nick P., Das, Raj, Ford, Ian, Henderson, Robert A., Junejo, Shahid, Layland, Jamie, Oldroyd, Keith G., Sood, Arvind   +10 more
core   +1 more source

Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]

, 2018
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin, Corcoran, David, Ford, Thomas J.   +2 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Three-Dimensional Angiographic Characteristics versus Functional Stenosis Severity in Fractional and Coronary Flow Reserve Discordance: A DEFINE FLOW Sub Study

Diagnostics, 2022
Background: Coronary angiography alone is insufficient to identify lesions associated with myocardial ischemia that may benefit from revascularization.
Valerie Stegehuis, Jelmer Westra, Coen Boerhout, Martin Sejr-Hansen, Ashkan Eftekhari, Hernan Mejía-Renteria, Maribel Cambero-Madera, Niels Van Royen, Hitoshi Matsuo, Masafumi Nakayama, Maria Siebes, Evald Høj Christiansen, Tim Van de Hoef, Jan Piek   +13 more
doaj   +1 more source

Failed ISCHEMIA Trial or Failed Ischemia Testing? [PDF]

, 2020
The results of the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approach) trial were presented at the American Heart Association Scientific Sessions in November, 2019 in Philadelphia, Pennsylvania, and ...
Budoff, Matthew J, Dahal, Suraj
core  

Computational fluid dynamics modeling of symptomatic intracranial atherosclerosis may predict risk of stroke recurrence. [PDF]

, 2014
BackgroundPatients with symptomatic intracranial atherosclerosis (ICAS) of ≥ 70% luminal stenosis are at high risk of stroke recurrence. We aimed to evaluate the relationships between hemodynamics of ICAS revealed by computational fluid dynamics (CFD ...
Chen, Xiangyan, Fan, Florence SY, Feldmann, Edward, Fong, Albert K, Ip, Hing Lung, Johnson, Mark, Leng, Xinyi, Leung, Thomas WH, Liebeskind, David S, Liu, Liping, Miao, Zhongrong, Scalzo, Fabien, Soo, Yannie OY, Wong, Ka Sing   +13 more
core   +3 more sources

Fractional flow reserve: a clinical perspective [PDF]

The International Journal of Cardiovascular Imaging, 2017
Fractional flow reserve (FFR) is a reference invasive diagnostic test to assess the physiological significance of an epicardial coronary artery stenosis. FFR-guided percutaneous coronary intervention in stable coronary artery disease has been assessed in three seminal clinical trials and the indications for FFR assessment are expanding into other ...
Corcoran, David, Hennigan, Barry, Berry, Colin   +2 more
openaire   +3 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: Mid-term outcomes from the CECaT randomised controlled trial [PDF]

, 2014
Objectives: To compare outcomes and cost-effectiveness of various initial imaging strategies in the management of stable chest pain in a long-term prospective randomised trial.
Buxton, Martin, CECaT study group, Crean, Andrew M, Dyer, Matthew, Hughes, Vikki, Jackson, Christopher H, Sharples, Linda D, Thom, Howard, West, Nicholas EJ   +8 more
core   +2 more sources