Results 41 to 50 of about 225,962 (269)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A comprehensive review of the Pachpatte-type inequality pertaining to fractional integral operators [PDF]

Surveys in Mathematics and its Applications
In the frame of fractional calculus, the term convexity is primarily utilized to address several challenges in both pure and applied research. The main focus and objective of this review paper is to present Pachpatte-type inequalities involving a variety
Muhammad Tariq, Asif Ali Shaikh, Sotiris K. Ntouyas   +2 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Ostrowski type inequalities for harmonically s-convex functions via fractional integrals [PDF]

, 2013
In this paper, a new identity for fractional integrals is established. Then by making use of the established identity, some new Ostrowski type inequalities for harmonically s-convex functions via Riemann--Liouville fractional integral are established ...
Iscan, Imdat
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Fractional Calculus of Fractal Interpolation Function on [0,b](b>0)

Abstract and Applied Analysis, 2014
The paper researches the continuity of fractal interpolation function’s fractional order integral on [0,+∞) and judges whether fractional order integral of fractal interpolation function is still a fractal interpolation function on [0,b](b>0) or not ...
XueZai Pan
doaj   +1 more source

On local fractional integral inequalities via generalized (h˜1,h˜2)\left({\tilde{h}}_{1},{\tilde{h}}_{2})-preinvexity involving local fractional integral operators with Mittag-Leffler kernel

Demonstratio Mathematica, 2023
Local fractional integral inequalities of Hermite-Hadamard type involving local fractional integral operators with Mittag-Leffler kernel have been previously studied for generalized convexities and preinvexities.
Vivas-Cortez Miguel, Bibi Maria, Muddassar Muhammad, Al-Sa’di Sa’ud   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Existence of solutions of coupled φ-Hilfer fractional differential systems with integral boundary conditions [PDF]

Journal of Hebei University of Science and Technology
In order to expand the relevant theory of fractional differential equation systems, a class of coupled φ-Hilfer fractional differential systems with integral boundary conditions was studied.
Bei ZHANG, Huanmin SI, Weihua JIANG, Chunjing GUO, Kun CHEN   +4 more
doaj   +1 more source