Results 41 to 50 of about 227,281 (268)

A comprehensive review of the Pachpatte-type inequality pertaining to fractional integral operators [PDF]

open access: yesSurveys in Mathematics and its Applications
In the frame of fractional calculus, the term convexity is primarily utilized to address several challenges in both pure and applied research. The main focus and objective of this review paper is to present Pachpatte-type inequalities involving a variety
Muhammad Tariq   +2 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

On the integral of fractional Poisson processes [PDF]

open access: yesStatistics & Probability Letters, 2013
In this paper we consider the Riemann--Liouville fractional integral $\mathcal{N}^{α,ν}(t)= \frac{1}{Γ(α)} \int_0^t (t-s)^{α-1}N^ν(s) \, \mathrm ds $, where $N^ν(t)$, $t \ge 0$, is a fractional Poisson process of order $ν\in (0,1]$, and $α> 0$. We give the explicit bivariate distribution $\Pr \{N^ν(s)=k, N^ν(t)=r \}$, for $t \ge s$, $r \ge k$, the ...
E. Orsingher, POLITO, Federico
openaire   +4 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Existence of solutions of coupled φ-Hilfer fractional differential systems with integral boundary conditions [PDF]

open access: yesJournal of Hebei University of Science and Technology
In order to expand the relevant theory of fractional differential equation systems, a class of coupled φ-Hilfer fractional differential systems with integral boundary conditions was studied.
Bei ZHANG   +4 more
doaj   +1 more source

On local fractional integral inequalities via generalized (h˜1,h˜2)\left({\tilde{h}}_{1},{\tilde{h}}_{2})-preinvexity involving local fractional integral operators with Mittag-Leffler kernel

open access: yesDemonstratio Mathematica, 2023
Local fractional integral inequalities of Hermite-Hadamard type involving local fractional integral operators with Mittag-Leffler kernel have been previously studied for generalized convexities and preinvexities.
Vivas-Cortez Miguel   +3 more
doaj   +1 more source

Calculus of variations with fractional derivatives and fractional integrals

open access: yesApplied Mathematics Letters, 2009
We prove Euler-Lagrange fractional equations and sufficient optimality conditions for problems of the calculus of variations with functionals containing both fractional derivatives and fractional integrals in the sense of Riemann-Liouville.
Ricardo Almeida 0001   +1 more
openaire   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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