Results 41 to 50 of about 1,361,829 (303)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Fractional generalization of Kac integral [PDF]
Communications in Nonlinear Science and Numerical Simulation, 2008 Generalization of the Kac integral and Kac method for paths measure based on the Levy distribution has been used to derive fractional diffusion equation. Application to nonlinear fractional Ginzburg-Landau equation is discussed.
Tarasov, Vasily E., Zaslavsky, George M.
openaire +2 more sources
, 2021 Integral equations and inequalities have an important place in time scales and harmonic analysis. The norm of integral operators is one of the important study topics in harmonic analysis.
Akın, Lütfi
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Some new results on hermite-hadamard-mercer-type inequalities using a general family of fractional integral operators [PDF]
, 2021 The aim of this article is to obtain new Hermite-Hadamard-Mercer-type inequalities using Raina's fractional integral operators. We present some distinct and novel fractional Hermite-Hadamard-Mercer-type inequalities for the functions whose absolute value
Set, Erhan, Aslan, Mucahit, Celik, Baris
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Fractional integration and data frequency [PDF]
Journal of Statistical Computation and Simulation, 2009 This paper examines the robustness of fractional integration estimates to different data frequencies. We show by means of Monte Carlo experiments that if the number of differences is an integer value (e.g. 0 or 1), there is no distortion when data are collected at wider intervals; however, if it is a fractional value, the distortion increases as the ...
Luis A. Gil-Alana, Guglielmo M. Caporale
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Random fractional Fourier transform : stochastic perturbations along the axis of propagation [PDF]
, 1999 The fractional Fourier transform (FRT) is known to be optically implementable with use of a medium with a perfect radial quadratic-index profile. Using the quantum-mechanical operator formalism, we examine the effects on the FRT action of such a medium
Abe, Sumiyoshi, Sheridan, John T.
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source