Results 61 to 70 of about 73,328 (276)

Extended Riemann-Liouville fractional derivative operator and its applications [PDF]

open access: yes, 2015
Many authors have introduced and investigated certain extended fractional derivative operators. The main object of this paper is to give an extension of the Riemann-Liouville fractional derivative operator with the extended Beta function given by ...
Agarwal, Praveen   +2 more
core   +1 more source

On the Multilinear Fractional Integral Operators with Correlation Kernels [PDF]

open access: yesJournal of Fourier Analysis and Applications, 2017
42 pages. A new proof by Brascamp-Lieb inequality is given in this version.
Shi, Zuoshunhua, Wu, Di, Yan, Dunyan
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

On a Generalized Laguerre Operational Matrix of Fractional Integration [PDF]

open access: yesMathematical Problems in Engineering, 2013
A new operational matrix of fractional integration of arbitrary order for generalized Laguerre polynomials is derived. The fractional integration is described in the Riemann-Liouville sense. This operational matrix is applied together with generalized Laguerre tau method for solving general linear multiterm fractional differential equations (FDEs). The
Bhrawy, A. H.   +3 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A new fractional derivative involving the normalized sinc function without singular kernel

open access: yes, 2017
In this paper, a new fractional derivative involving the normalized sinc function without singular kernel is proposed. The Laplace transform is used to find the analytical solution of the anomalous heat-diffusion problems. The comparative results between
Baleanu, Dumitru   +3 more
core   +1 more source

Minkowski’s inequality for the AB-fractional integral operator [PDF]

open access: yesJournal of Inequalities and Applications, 2019
Recently, AB-fractional calculus has been introduced by Atangana and Baleanu and attracted a large number of scientists in different scientific fields for the exploration of diverse topics. An interesting aspect is the generalization of classical inequalities via AB-fractional integral operators. In this paper, we aim to generalize Minkowski inequality
Hasib Khan   +4 more
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Sharp weighted bounds for one-sided and multiple integral operators [PDF]

open access: yes, 2014
In this paper we establish sharp weighted bounds (Buckley type theorems) for one{sided maximal and fractional integral operators in terms of one{sided $A_p$ characteristics.
Kokilashvili, Vakhtang   +2 more
core  

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