Results 91 to 100 of about 1,437,498 (311)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

New version of midpoint-type inequalities for co-ordinated convex functions via generalized conformable integrals

Boundary Value Problems
In the current research, some midpoint-type inequalities are generalized for co-ordinated convex functions with the help of generalized conformable fractional integrals.
Mehmet Eyüp Kiriş, Miguel Vivas-Cortez, Tuğba Yalçin Uzun, Gözde Bayrak, Hüseyin Budak   +4 more
doaj   +1 more source

Simpson’s type integral inequalities for ĸ-fractional integrals and their applications

AIMS Mathematics, 2019
In this paper, some new inequalities of Simpson's type are set up for the classes of functions whose derivatives of absolute are preinvex by means of ĸ-fractional integrals.
S. Rashid, A. Akdemi̇r, F. Jarad, M. Noor, K. Noor   +4 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Advancements in corrected Euler–Maclaurin-type inequalities via conformable fractional integrals

Boundary Value Problems
In this research article, equality is proved to obtain corrected Euler–Maclaurin-type inequalities. Using this identity, we establish several corrected Euler–Maclaurin-type inequalities for the case of differentiable convex functions by means of ...
Yaren Acar, Hüseyin Budak, Umut Bas, Fatih Hezenci, Hüseyin Yıldırım   +4 more
doaj   +1 more source

Conformable Fractional Integrals Versions of Hermite-Hadamard Inequalities and Their Generalizations

Journal of Function Spaces, 2018
We prove new Hermite-Hadamard inequalities for conformable fractional integrals by using convex function, s-convex, and coordinate convex functions. We prove new Montgomery identity and by using this identity we obtain generalized Hermite-Hadamard type ...
M. Adil Khan, Y. Chu, A. Kashuri, Rozana Liko, Gohar Ali   +4 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Hermite–Hadamard-Type Inequalities for Convex Functions via the Fractional Integrals with Exponential Kernel

Mathematics, 2019
In this paper, we establish three fundamental integral identities by the first- and second-order derivatives for a given function via the fractional integrals with exponential kernel.
Xia Wu, Jinrong Wang, Jialu Zhang
semanticscholar   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Sharp function estimates and boundedness for Toeplitz-type operators associated with general fractional integral operators [PDF]

, 2021
Dazhao Chen, Hui Huang
openalex   +1 more source