Results 31 to 40 of about 3,783 (264)

On multiplicative conformable fractional integrals: theory and applications

open access: yesBoundary Value Problems
In this paper, we first introduce the multiplicative conformable left and right fractional integrals, followed by the derivation of key properties, such as integrability, boundedness, continuity, and the semi-group property, for the newly defined ...
Hüseyin Budak, Büşra Betül Ergün
doaj   +1 more source

On generalized stochastic fractional integrals and related inequalities

open access: yesModern Stochastics: Theory and Applications, 2018
The generalized mean-square fractional integrals ${\mathcal{J}_{\rho ,\lambda ,u+;\omega }^{\sigma }}$ and ${\mathcal{J}_{\rho ,\lambda ,v-;\omega }^{\sigma }}$ of the stochastic process X are introduced.
Hüseyin Budak, Mehmet Zeki Sarikaya
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

New Approaches to Fractal–Fractional Bullen’s Inequalities Through Generalized Convexity

open access: yesFractal and Fractional
This paper introduces a new identity involving fractal–fractional integrals, which allow us to derive several new Bullen-type inequalities via generalized convexity.
Wedad Saleh   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Midpoint-type inequalities via twice-differentiable functions on tempered fractional integrals

open access: yesJournal of Inequalities and Applications, 2023
In this paper, we obtain an equality involving tempered fractional integrals for twice-differentiable functions. By using this equality, we establish several left Hermite–Hadamard-type inequalities for the case of tempered fractional integrals. Moreover,
Fatih Hezenci, Hüseyin Budak
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Newton-type Inequalities for Fractional Integrals by Various Function Classes

open access: yesUniversal Journal of Mathematics and Applications
The authors of the paper examine some Newton-type inequalities for various function classes using Riemann-Liouville fractional integrals. Namely, we establish some Newton-type inequalities for bounded functions by fractional integrals.
Hüseyin Budak   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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