Results 41 to 50 of about 3,783 (264)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Some New Approaches to Fractional Euler–Maclaurin-Type Inequalities via Various Function Classes
This paper aims to examine an approach that studies many Euler–Maclaurin-type inequalities for various function classes applying Riemann–Liouville fractional integrals.
Mehmet Gümüş +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Certain inequalities via generalized proportional Hadamard fractional integral operators
In the article, we introduce the generalized proportional Hadamard fractional integrals and establish several inequalities for convex functions in the framework of the defined class of fractional integrals.
Gauhar Rahman +4 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Fractional Definite Integral [PDF]
This paper proposes the definition of fractional definite integral and analyses the corresponding fundamental theorem of fractional calculus. In this context, we studied the relevant properties of the fractional derivatives that lead to such a definition. Finally, integrals on R2 R 2 and R3 R 3 are also proposed.
Manuel Ortigueira, José Machado
openaire +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Partial, Composite Fractional Operators, and Their Properties and Applications
The paper discusses the properties of the partial fractional integrals, the partial fractional derivatives, and the composite fractional integrals and derivatives.
Deng Kaiying, Deng Jingwei, Li Suduo
doaj +1 more source
Elements of fractional calculus. Fractional integrals
The paper is devoted to the basic properties of fractional integrals. It is a survey of the well-known properties of fractional integrals, however, the authors tried to present the known information about fractional integrals as short and transparently as possible. We introduce fractional integrals on the compact interval and on the semi-axes, consider
Yuliya Mishura +2 more
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

