Results 61 to 70 of about 6,726 (311)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On the integral of fractional Poisson processes [PDF]
Statistics & Probability Letters, 2013 In this paper we consider the Riemann--Liouville fractional integral $\mathcal{N}^{α,ν}(t)= \frac{1}{Γ(α)} \int_0^t (t-s)^{α-1}N^ν(s) \, \mathrm ds $, where $N^ν(t)$, $t \ge 0$, is a fractional Poisson process of order $ν\in (0,1]$, and $α> 0$. We give the explicit bivariate distribution $\Pr \{N^ν(s)=k, N^ν(t)=r \}$, for $t \ge s$, $r \ge k$, the ...
ORSINGHER, Enzo, POLITO, FEDERICO
openaire +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Some New Approaches to Fractional Euler–Maclaurin-Type Inequalities via Various Function Classes
Fractal and FractionalThis paper aims to examine an approach that studies many Euler–Maclaurin-type inequalities for various function classes applying Riemann–Liouville fractional integrals.
Mehmet Gümüş +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Certain inequalities via generalized proportional Hadamard fractional integral operators
Advances in Difference Equations, 2019 In the article, we introduce the generalized proportional Hadamard fractional integrals and establish several inequalities for convex functions in the framework of the defined class of fractional integrals.
Gauhar Rahman +4 more
doaj +1 more source
Calculus of variations with fractional derivatives and fractional integrals
Applied Mathematics Letters, 2009 We prove Euler-Lagrange fractional equations and sufficient optimality conditions for problems of the calculus of variations with functionals containing both fractional derivatives and fractional integrals in the sense of Riemann-Liouville.
Ricardo Almeida 0001 +1 more
openaire +4 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Partial, Composite Fractional Operators, and Their Properties and Applications
MATEC Web of Conferences, 2017 The paper discusses the properties of the partial fractional integrals, the partial fractional derivatives, and the composite fractional integrals and derivatives.
Deng Kaiying, Deng Jingwei, Li Suduo
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source