Results 71 to 80 of about 1,437,498 (311)

On generalized stochastic fractional integrals and related inequalities

Modern Stochastics: Theory and Applications, 2018
The generalized mean-square fractional integrals ${\mathcal{J}_{\rho ,\lambda ,u+;\omega }^{\sigma }}$ and ${\mathcal{J}_{\rho ,\lambda ,v-;\omega }^{\sigma }}$ of the stochastic process X are introduced.
Hüseyin Budak, Mehmet Zeki Sarikaya
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Newton-type Inequalities for Fractional Integrals by Various Function Classes

Universal Journal of Mathematics and Applications
The authors of the paper examine some Newton-type inequalities for various function classes using Riemann-Liouville fractional integrals. Namely, we establish some Newton-type inequalities for bounded functions by fractional integrals.
Hüseyin Budak, Tingsong Du, Fatih Hezenci   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Integral inequalities via Raina’s fractional integrals operator with respect to a monotone function

, 2020
We establish certain new fractional integral inequalities involving the Raina function for monotonicity of functions that are used with some traditional and forthright inequalities.
Shu-Bo Chen, S. Rashid, Z. Hammouch, M. Noor, Rehan Ashraf, Y. Chu   +5 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Some New Approaches to Fractional Euler–Maclaurin-Type Inequalities via Various Function Classes

Fractal and Fractional
This paper aims to examine an approach that studies many Euler–Maclaurin-type inequalities for various function classes applying Riemann–Liouville fractional integrals.
Mehmet Gümüş, Fatih Hezenci, Hüseyin Budak   +2 more
doaj   +1 more source

Hermite-Jensen-Mercer type inequalities via Ψ-Riemann-Liouville k-fractional integrals

AIMS Mathematics, 2020
Integral inequalities involving various fractional integral operators are used to solve many fractional differential equations. In this paper, authors prove some Hermite-Jensen-Mercer type inequalities using Ψ-Riemann-Liouville k-Fractional integrals via
Saad Ihsan Butt, Artion Kashuri, Muhammad Umar, Adnan Aslam, Wei Gao   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source