Results 51 to 60 of about 176,088 (217)

A Caputo (discretization) fractional-order model of glucose-insulin interaction: numerical solution and comparisons with experimental data

open access: yesJournal of Taibah University for Science, 2021
In this paper, we investigate a (discretization) Caputo fractional glucose-insulin model qualitatively with incommensurate orders that appear in Bergman's minimal model.
Mansoor H. Alshehri   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Характеристики деформационного процесса в зоне субдукции Курило-Камчатской островной дуги в фазе афтершоков на основе дробной модели деформационной активности

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki
В статье представлены результаты расчётов значений параметров, определяющих свойства деформационного процесса, на основании данных каталога землетрясений Камчатского филиала ФГБУН Федеральный исследовательский центр «Единая геофизическая служба РАН» (КФ ...
Шереметьева, О.В.   +1 more
doaj   +1 more source

Research on Population Development Trend in Huizhou of China Forecast Based on Optimal Weighted Combination Method and Fractional Grey Model

open access: yesJournal of Mathematics, 2021
In this paper, the optimal weighted combination model and fractional grey model are constructed. The coefficients of the optimal weighted combination model are determined by minimizing the sum of squares of resists of each model.
Dewang Li, Jianbao Chen, Meilan Qiu
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Приложение дробной модели деформационной активности к исследованию свойств эредитарности и нестационарности сейсмического процесса в зоне субдукции Курило-Камчатской островной дуги в фазе релаксации

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki
Исследование свойств эредитарности и нестационарности сейсмического процесса в фазе релаксации проводится на основании данных каталога землетрясений КФ ЕГС РАН (01.01.1962 − 31.12.2002, зона субдукции Курило-Камчатской островной дуги).
Шереметьева, О.В.   +1 more
doaj   +1 more source

Analysis and Modeling of Fractional-Order Buck Converter Based on Riemann-Liouville Derivative

open access: yesIEEE Access, 2019
In previous studies, researchers used the fractional definition of Caputo to study fractional-order power converter. However, it is found that the model based on Caputo fractional definition is inconsistent with the actual situation.
Zhihao Wei, Bo Zhang, Yanwei Jiang
doaj   +1 more source

Development of Fractional Order Modeling of Voltage Source Converters

open access: yesIEEE Access, 2020
This paper proposes a mathematical fractional order modelling of Voltage Source Converters (VSC). Fractional behaviour helps to model and describe a real object more accurately than the integer order model.
Monika Sharma   +3 more
doaj   +1 more source

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