Results 51 to 60 of about 176,088 (217)
In this paper, we investigate a (discretization) Caputo fractional glucose-insulin model qualitatively with incommensurate orders that appear in Bergman's minimal model.
Mansoor H. Alshehri +3 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
В статье представлены результаты расчётов значений параметров, определяющих свойства деформационного процесса, на основании данных каталога землетрясений Камчатского филиала ФГБУН Федеральный исследовательский центр «Единая геофизическая служба РАН» (КФ ...
Шереметьева, О.В. +1 more
doaj +1 more source
In this paper, the optimal weighted combination model and fractional grey model are constructed. The coefficients of the optimal weighted combination model are determined by minimizing the sum of squares of resists of each model.
Dewang Li, Jianbao Chen, Meilan Qiu
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Исследование свойств эредитарности и нестационарности сейсмического процесса в фазе релаксации проводится на основании данных каталога землетрясений КФ ЕГС РАН (01.01.1962 − 31.12.2002, зона субдукции Курило-Камчатской островной дуги).
Шереметьева, О.В. +1 more
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Analysis and Modeling of Fractional-Order Buck Converter Based on Riemann-Liouville Derivative
In previous studies, researchers used the fractional definition of Caputo to study fractional-order power converter. However, it is found that the model based on Caputo fractional definition is inconsistent with the actual situation.
Zhihao Wei, Bo Zhang, Yanwei Jiang
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Development of Fractional Order Modeling of Voltage Source Converters
This paper proposes a mathematical fractional order modelling of Voltage Source Converters (VSC). Fractional behaviour helps to model and describe a real object more accurately than the integer order model.
Monika Sharma +3 more
doaj +1 more source

