Results 61 to 70 of about 176,088 (217)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Предвестники землетрясений в теории критичности геодеформаций

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki
Предвестники землетрясений рассматриваются как резонансные проявления критических геодеформаций, дислокационные изменения которых отвечают за аномальные свойства, как самих деформаций, так и порожденных ими физических процессов, играющих роль индикаторов
Шевцов, Б.М.   +1 more
doaj   +1 more source

Fractal Dynamics and Control of the Fractional Potts Model on Diamond-Like Hierarchical Lattices

open access: yesDiscrete Dynamics in Nature and Society, 2020
The fractional Potts model on diamond-like hierarchical lattices is introduced in this manuscript, which is a fractional rational system in the complex plane. Then, the fractal dynamics of this model is discussed from the fractal viewpoint.
Weihua Sun, Shutang Liu
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Analysis of Drude model using fractional derivatives without singular kernels

open access: yesOpen Physics, 2017
We report study exploring the fractional Drude model in the time domain, using fractional derivatives without singular kernels, Caputo-Fabrizio (CF), and fractional derivatives with a stretched Mittag-Leffler function.
Jiménez Leonardo Martínez   +3 more
doaj   +1 more source

Chaotic Dynamics of the Fractional-Love Model with an External Environment

open access: yesEntropy, 2018
Based on the fractional order of nonlinear system for love model with a periodic function as an external environment, we analyze the characteristics of the chaotic dynamic.
Linyun Huang, Youngchul Bae
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Inertial Memory Effects in Molecular Transport Across Nanoporous Membranes

open access: yesMembranes
Nanoporous membranes are heterogeneous structures, with heterogeneity manifesting at the microscale. In examining particle transport through such media, it has been observed that this transport deviates from classical diffusion, as described by Fick’s ...
Slobodanka Galovic   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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