Results 41 to 50 of about 5,262 (258)
Lévy Processes Linked to the Lower-Incomplete Gamma Function
We start by defining a subordinator by means of the lower-incomplete gamma function. This can be considered as an approximation of the stable subordinator, easier to be handled in view of its finite activity.
Luisa Beghin, Costantino Ricciuti
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Application of the Complex Moments for Selection of an Optimal Sensor
In the first time we apply the statistics of the complex moments for selection of an optimal pressure sensor (from the available set of sensors) based on their statistical/correlation characteristics.
Raoul R. Nigmatullin +1 more
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Lognormal Distribution Is Characterized by Its Integer Moments
The lognormal moment sequence is considered. Using the fractional moments technique, it is first proved that the lognormal has the largest differential entropy among the infinite positively supported probability densities with the same lognormal-moments.
Pier Luigi Novi Inverardi, Aldo Tagliani
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
This article introduces the design of symmetrical approximately shift-invariant fractional overcomplete wavelet transforms. First, a design scheme for the symmetrical low-pass filter with minimum-length was proposed, and then the corresponding highpass ...
SHEN Zheng-wei, SHI Tian, SHEN Ya-nan
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Chaotic systems are widely used in signal and image encryption schemes. Therefore, the design of new chaotic systems is always useful for improving the performance of encryption schemes in terms of security. In this work, we first demonstrate the chaotic
Achraf Daoui +6 more
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