Results 141 to 150 of about 24,943,460 (295)

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Existence and multiplicity of solutions for fractional p-Laplacian equation involving critical concave-convex nonlinearities

Advanced Nonlinear Studies
We investigate the following fractional p-Laplacian convex-concave problem:(Pλ)(−Δ)psu=λ|u|q−2u+|u|ps*−2u inΩ,u=0 inRn\Ω,  $$\left({P}_{\lambda }\right) \begin{cases}\begin{aligned}\hfill {\left(-{\Delta}\right)}_{p}^{s}u& =\lambda \vert u{\vert
Ye Dong, Zhang Weimin
doaj   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Chiral Supramolecular Templating Enables Tunable Second‐Harmonic Generation in Hybrid Zinc Thiocyanates

Angewandte Chemie, EarlyView.
Chiral supramolecular templates derived from natural amino acids direct the spatial organization of SHG‐active [Zn(SCN)4]2− units, enabling diverse second‐harmonic generation in hybrid zinc thiocyanates. ABSTRACT Chiral organic molecules have been widely used to construct hybrid nonlinear optical (NLO) materials with second‐harmonic generation (SHG ...
Xuemei Wen, Qinglan Zhong, Gangji Yi, Guohong Zou, Jianli Wang, Zhien Lin, Kang Min Ok   +6 more
wiley   +2 more sources

High‐Responsivity and Fast‐Response Organic Phototransistor Based on Dinaphtho[2,3‐b:2′,3′‐f]Thieno[3,2‐b]Thiophene

Advanced Electronic Materials, EarlyView.
Low‐temperature Al/Al2O3/DNTT/Au organic phototransistors fabricated on flexible PEN combine high responsivity to blue light (≈250 A W−1 at 39 nW cm−2) with detectable modulated photoresponse up to 150 kHz, making them promising for ultra‐low‐light sensing and moderate‐speed optical links.
Antonio Caldarelli, Antonio Vettoliere, Paolo Scotto Di Vettimo, Marcello Campajola, Gino Giusi, Vincenzo Izzo, Alberto Aloisio, Ettore Sarnelli   +7 more
wiley   +1 more source

A de‐novo Approach Towards Divergent [3+2π/σ] Photocycloadditions of Nitrones via Assembly‐Controlled Kinetic Electron Transfer Gating

Angewandte Chemie, EarlyView.
A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha, Rajesh Kancherla, Jorge Escorihuela, Shana Chandran, Mrinal K. Bera, Magnus Rueping, Burkhard König   +6 more
wiley   +2 more sources

Competing Charge Separation Pathways Govern Charge Generation in Organic Photovoltaic Blends: Insights From Transient Electron Spin Resonance

Advanced Energy Materials, EarlyView.
Transient electron spin resonance distinguishes interfacial charge‐transfer states from separated charges, revealing competing charge separation pathways in organic photovoltaic blends. The relative contributions of fast charge separation and a pathway mediated by spin‐polarized charge‐transfer states vary across different blends, with high‐efficiency ...
Jack M. S. Palmer, Claudia E. Tait
wiley   +1 more source

Diblock Copolymer Nanoparticles Act as Nanoreactors for the Synthesis of Sterically‐Stabilized Inorganic Oxide Particles in Non‐polar Media

Angewandte Chemie, EarlyView.
Poly(lauryl methacrylate)‐poly(2‐hydroxyethyl methacrylate) (PLMA‐PHEMA) diblock copolymer nanoparticles prepared in non‐polar media serve as nanoreactors for the in situ synthesis of silica from tetraethyl orthosilicate (TEOS). A silica mass loading of 17% as judged by thermogravimetric analysis (TGA) produces a highly transparent dispersion, and ...
Priyanka Chohan, Andi Xie, Oleksandr O. Mykhaylyk, Steven P. Armes, Giles M. Prentice, David J. Atkinson, Andrew J. Smith   +6 more
wiley   +2 more sources

A Breadth‐First Pruned‐Enriched Rosenbluth Method for Force–Extension Simulations of Confined Semiflexible Chains

Advanced Intelligent Discovery, EarlyView.
The behaviors of semiflexible polymers such as DNA and protein are often reshaped by coupled interactions. Monte Carlo simulations assist in studying these systems. This work recasts the traditional chain‐growth strategy into a new framework: a fixed number of chains grow synchronously, while less relevant chains to the target system are removed and ...
Yihan Zhao, Jizeng Wang
wiley   +1 more source

Epitaxial Oxide Interfaces Create Poison‐Resistant CuO Sites for Environmental Catalysis

Angewandte Chemie, EarlyView.
An epitaxially stabilized CuO overlayer on Ti1−xInxO2 creates electron‐poor, high‐symmetry Cu–O sites that activate interfacial lattice‐oxygen redox. This interface promotes NOx reduction through an Eley–Rideal pathway, diverts sulfate formation, and sustains CH3SH deep oxidation via a Mars–van Krevelen cycle, offering a route to poison‐resistant ...
Lupeng Han, Yanqing Li, Yongjie Shen, Huijun Yu, Evangelina Pensa, Xuehui Yang, Yanqi Chen, Xiaonan Hu, Xiyang Wang, Song Li, Gaowu Qin, Wenqiang Qu, Ming Xie, Emiliano Cortés, Dengsong Zhang   +14 more
wiley   +2 more sources