Results 121 to 130 of about 24,943,460 (295)

Qualitative properties of solutions to generalized eigenvalue problems [PDF]

Arab Journal of Mathematical Sciences
PurposeThis paper investigates the qualitative properties of solutions to a fractional (p,)-Laplace eigenvalue problem with nonhomogeneous terms.
Abdelhamid Gouasmia, Oumaima Ouennas, Amel Bekhouche   +2 more
doaj   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Existence of solutions for non-local elliptic systems with Hardy-Littlewood-Sobolev critical nonlinearities

Electronic Journal of Differential Equations, 2019
In this work, we establish the existence of solutions for the nonlinear nonlocal system of equations involving the fractional Laplacian, \begin{gather*} \begin{aligned} (-\Delta)^s u & = au+bv+\frac{2p}{p+q}\int_{\Omega}\frac{|v(y)|^q}{|x-y|^\mu}dy|
Yang Yang, Qian Yu Hong, Xudong Shang
doaj  

Existence and regularity for elliptic equations under p,q-growth

, 2014
Under general p,q-growth conditions, we prove that the Dirichlet problem \[\sum_{i=1}^{n}D_{x_{i}}(a^{i}(x,Du))=b(x) \text{in}\,\Omega , u=u_{0} \text{on}\,\partial \Omega\] has a weak solution $u\in W_{loc}^{1,q}(\Omega)$ under the assumptions ...
CUPINI, GIOVANNI, P. Marcellini, E. Mascolo   +2 more
core  

The second Hyper-Zagreb index of VC5C7 [p, q] and HC5C7 [p, q] nanotubes

The first and second Hyper-Zagreb indices are the molecular descriptors that describe the structures of chemical compounds and they help us to predict certain physicochemical properties. In this paper, we studied the first and second Hyper-Zagreb indices
ZEREN, Yusuf, Alameri, Abdu Q., Alsharafi, Mohammed S. Y.   +2 more
core   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source

Normalized solutions for a class of fractional Choquard equations with mixed nonlinearities

Demonstratio Mathematica
In this paper we study the following fractional Choquard equation with mixed nonlinearities:(−Δ)su=λu+αIμ∗|u|q|u|q−2u+Iμ∗|u|p|u|p−2u,x∈RN,∫RN|u|2dx=c2>0.
Chen Shaoxiong, Yang Zhipeng, Zhang Xi
doaj   +1 more source

Positive solutions to fractional boundary-value problems with p-Laplacian on time scales

Boundary Value Problems, 2018
In this article, we consider the following boundary-value problem of nonlinear fractional differential equation with p-Laplacian operator: Dα(ϕp(Dαu(t)))=f(t,u(t)),t∈[0,1]T,u(0)=u(σ(1))=Dαu(0)=Dαu(σ(1))=0, $$\begin{aligned}& D^{\alpha }\bigl(\phi_{p ...
Kai Sheng, Wei Zhang, Zhanbing Bai
doaj   +1 more source

Some Caputo k-fractional derivatives of Ostrowski type concerning (n+1)-differentiable generalized relative semi-(r;m,p,q,h₁,h₂)-preinvex mappings

, 2018
In this article, we first presented some integral inequalities for Gauss-Jacobi type quadrature formula involving generalized relative semi-(r;m,p,q,h₁,h₂)-preinvex mappings.
A. Kashuri, Rozana Liko
semanticscholar   +1 more source