Results 91 to 100 of about 84,498 (293)

Duality in Fractional Programming Involving Locally Arcwise Connected and Related Functions [PDF]

A nonlinear fractional programming problem is considered, where the functions involved are diferentiable with respect to an arc.Necessary and su±cient optimality conditions are obtained in terms of the right diferentials with respect to an arc of the ...
Emilio Cerdá, I.M. Stancu-Minasian, M.M. Muñoz, R. Caballero   +3 more
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Cutting plane methods for general integer programming [PDF]

, 1993
Integer programming (IP) problems are difficult to solve due to the integer restrictions imposed on them. A technique for solving these problems is the cutting plane method.
Darby-Dowman, K, Hamid, FA, Mitra, G
core  

A hybrid constraint programming and semidefinite programming approach for the stable set problem

, 2003
This work presents a hybrid approach to solve the maximum stable set problem, using constraint and semidefinite programming. The approach consists of two steps: subproblem generation and subproblem solution.
B. Borchers, C. Helmberg, C.H. Papadimitriou, E. Halperin, F. Alizadeh, F. Focacci, G. Gruber, H. Sakkout El, H.C. Lau, I.M. Bomze, L. Lovász, M. Goemans, M. Grötschel, M. Milano, M.X. Goemans, P.M. Pardalos, S.E. Karisch, T. Fahle, W.J. Hoeve van   +18 more
core   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A new algorithm for generalized fractional programs [PDF]

A new dual problem for convex generalized fractional programs with no duality gap is presented and it is shown how this dual problem can be efficiently solved using a parametric approach. The resulting algorithm can be seen as “dual†to the Dinkelbach-
Barros, A.I., Frenk, J.B.G., Schaible, S., Zhang, S.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Branch and Bound Algorithm for a Discrete Multilevel Linear Fractional Programming Problem

Operations Research and Decisions, 2018
An algorithm is proposed to find an integer solution for bilevel linear fractional programming problem with discrete variables. The method develops a cut that removes the integer solutions which are not bilevel feasible.
Ritu Arora, Kavita Gupta
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

On the ratio of fuzzy numbers – exact membership function computation and applications to decision making

Technological and Economic Development of Economy, 2015
In the present paper, we propose a new approach to solving the full fuzzy linear fractional programming problem. By this approach, we provide a tool for making good decisions in certain problems in which the goals may be modelled by linear fractional ...
Bogdana Stanojević, Ioan Dziţac, Simona Dziţac   +2 more
doaj   +1 more source

Fractional coloring with local demands

, 2018
We investigate fractional colorings of graphs in which the amount of color given to a vertex depends on local parameters, such as its degree or the clique number of its neighborhood; in a \textit{fractional $f$-coloring}, vertices are given color from ...
Kelly, Tom, Postle, Luke
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