Results 71 to 80 of about 179,364 (266)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Mathematical Modelling and AnalysisThis paper investigates the fractional Keller-Segel system involving both temporal and spatial variables. We examine fractional dissipation mechanisms for the physical variables, including chemotactic diffusion with fractional dissipation, and ...
Hassan Khaider +2 more
doaj +1 more source
Advances in Mathematical Physics, 2019 In this paper, we present a corresponding fractional order three-dimensional autonomous chaotic system based on a new class of integer order chaotic systems.
Yan Cui +3 more
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Journal of Mathematics, 2020 In this paper, the authors consider a IBVP for the time-space fractional PDE with the fractional conformable derivative and the fractional Laplace operator. A fractional conformable extremum principle is presented and proved.
Tingting Guan, Guotao Wang
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Fractional Control of Dynamic Systems [PDF]
, 2011 The concepts involved with fractional calculus (FC) theory are applied in almost all areas of science and engineering. Its ability to yield superior modeling and control in many dynamical systems is well recognized. In this article, we will introduce the fundamental aspects associated with the application of FC to the control of dynamic systems.
Barbosa, Ramiro S. +1 more
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Quasiparticles with fractional charges in fractionally filled systems
Scientific ReportsAbstract We study systems that approach a state possessing discrete symmetry due to different degenerate realizations for the system. For concreteness, we consider fractionally filled systems where degeneracy comes from the presence of identical sub-lattices.
openaire +4 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source