Results 121 to 130 of about 347,722 (310)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Association between adeno‐associated virus genomic titers and intracellular plasmid levels

open access: yesEngineering Reports
The recombinant adeno‐associated viral (rAAV) vector is one of the most effective viral vectors in gene therapy because of its low immunogenicity, high transduction efficiency, broad tissue specificity, and long‐term transgene expression ability. HEK293T
Kyoko Masumi‐Koizumi   +4 more
doaj   +1 more source

On Fractional Laplacians

open access: yesCommunications in Partial Differential Equations, 2014
We compare two natural types of fractional Laplacians $(-Δ)^s$, "Navier" and "Dirichlet" ones.
MUSINA, Roberta, Nazarov A. I.
openaire   +3 more sources

Advection-dispersion in symmetric field-flow fractionation channels [PDF]

open access: yes, 1998
We model the evolution of the concentration field of macromolecules in a symmetric field-flow fractionation (FFF) channel by a one-dimensional advection-diffusion equation. The coefficients are precisely determined from the fluid dynamics.
Roberts, A. J., Suslov, Sergey A.
core  

Experimental study on isotope fractionation effects in visible photolysis of O3 and in the O+O3 odd oxygen sink reaction

open access: yes, 2015
International audienceInvestigation of isotope effects in ozone (O3) photolysis and its contribution to the overall ozone isotope composition is difficult since photolysis always leads to secondary O3 formation and O3 decomposition by reactions with O(3P)
Früchtl,, Marion   +10 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Fermentation-Guided Natural Products Isolation of a Grape Berry Triacylglyceride that Enhances Ethyl Ester Production

open access: yesMolecules, 2018
A full understanding of the origin, formation and degradation of volatile compounds that contribute to wine aroma is required before wine style can be effectively managed.
Christopher L. Blackford   +5 more
doaj   +1 more source

Altered fractionation radiotherapy in head and neck squamous cell carcinoma

open access: yes, 2016
IntroductionFractionation plays a pivotal role in determining the effectiveness of radiation and follows the principle of 4 “R” of radiobiology. The various altered fractionation schedules used are hyper-fractionation, accelerated fractionation, and hypo
Rony Benson   +3 more
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

A “SHort course Accelerated RadiatiON therapy” (SHARON) During and Beyond the COVID-19 Pandemic

open access: yesFrontiers in Oncology, 2022
Alessio G. Morganti   +10 more
doaj   +1 more source

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