Results 121 to 130 of about 347,722 (310)
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Association between adeno‐associated virus genomic titers and intracellular plasmid levels
The recombinant adeno‐associated viral (rAAV) vector is one of the most effective viral vectors in gene therapy because of its low immunogenicity, high transduction efficiency, broad tissue specificity, and long‐term transgene expression ability. HEK293T
Kyoko Masumi‐Koizumi +4 more
doaj +1 more source
We compare two natural types of fractional Laplacians $(-Δ)^s$, "Navier" and "Dirichlet" ones.
MUSINA, Roberta, Nazarov A. I.
openaire +3 more sources
Advection-dispersion in symmetric field-flow fractionation channels [PDF]
We model the evolution of the concentration field of macromolecules in a symmetric field-flow fractionation (FFF) channel by a one-dimensional advection-diffusion equation. The coefficients are precisely determined from the fluid dynamics.
Roberts, A. J., Suslov, Sergey A.
core
International audienceInvestigation of isotope effects in ozone (O3) photolysis and its contribution to the overall ozone isotope composition is difficult since photolysis always leads to secondary O3 formation and O3 decomposition by reactions with O(3P)
Früchtl,, Marion +10 more
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
A full understanding of the origin, formation and degradation of volatile compounds that contribute to wine aroma is required before wine style can be effectively managed.
Christopher L. Blackford +5 more
doaj +1 more source
Altered fractionation radiotherapy in head and neck squamous cell carcinoma
IntroductionFractionation plays a pivotal role in determining the effectiveness of radiation and follows the principle of 4 “R” of radiobiology. The various altered fractionation schedules used are hyper-fractionation, accelerated fractionation, and hypo
Rony Benson +3 more
core +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
A “SHort course Accelerated RadiatiON therapy” (SHARON) During and Beyond the COVID-19 Pandemic
Alessio G. Morganti +10 more
doaj +1 more source

