Results 51 to 60 of about 347,722 (310)

Insights into the Purification of C1-esterase Inhibitor from Human Plasma

Plasmatology
Hereditary angioedema (HAE) is a rare but often life-threatening genetic disorder caused by either lack of or dysfunctional C1-esterase inhibitor (C1-I3NH). C1-INH is a high-cost therapy for HAE.
Sachin Verma, Sheetal Dolia, Savan Makadia, Narendra Kumar   +3 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

LC-MS identification and preparative HPLC isolation of Frankenia pulverulenta phenolics with antioxidant and neuroprotective capacities in PC12 cell line

Pharmaceutical Biology, 2017
Context: Frankenia pulverulenta L. (Frankeniaceae) is a medicinal species with carminative, analgesic and antiviral properties. However, phytochemical investigations, antioxidant and neuroprotective capacities of this plant remain unclear.
Rim Ben Mansour, Megdiche Ksouri Wided, Stéphanie Cluzet, Stéphanie Krisa, Tristan Richard, Riadh Ksouri   +5 more
doaj   +1 more source

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

Characterization of heavy metal in soils as affected by long-term irrigation with industrial wastewater

Journal of Water Reuse and Desalination, 2019
Investigation of heavy metals (HM) fractions in soils irrigated with wastewater (WW) would ascertain their bioavailability and contamination level in soils. This study investigated HM fractions in soils after long-term WW irrigation.
Bushra Haroon, An Ping, Arshid Pervez, Faridullah, Muhammad Irshad   +4 more
doaj   +1 more source

Industrial applications and current trends in supercritical fluid technologies [PDF]

Hemijska Industrija, 2005
Supercritical fluids have a great potential for wide fields of processes Although CO2 is still one of the most used supercritical gases, for special purposes propane or even fluorinated-chlorinated fluids have also been tested.
Gamse Thomas
doaj   +1 more source

The fractional mixed fractional brownian motion and fractional brownian sheet [PDF]

ESAIM: Probability and Statistics, 2007
Summary: We introduce the fractional mixed fractional Brownian motion and fractional Brownian sheet, and investigate the small ball behavior of its sup-norm statistic. Then, we state general conditions and characterize the sufficiency part of the lower classes of some statistics of the above process by an integral test.
openaire   +2 more sources

A novel binary particle fractionation technique

, 2009
An interesting development towards a robust particle fractionator is presented. Typically acoustic fractionators rely on time of flight in a constant acoustic field to separate different populations .
Boltryk, R.J., Hill, M., Harris, N.R., Glynne-Jones, P., Harris, Nick, Hill, Martyn, Glynne-Jones, Peter, Boltryk, Rosemary   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fractionation of Allium giganteum Effective Extract on Gastrointestinal Neoplasms Cell Lines for Its Anti-Proliferative Properties

Advanced Biomedical Research
Background: This study was designed to investigate the various extracts of Allium giganteum in term of their cytotoxic effects on gastric and colon cancer cell lines and then fractionation of extract with the most desired effects on cancer cells in ...
Masoud Sadeghi Dinani, Mohammadreza Ghanbarzadeh, Fatemeh Shafiee   +2 more
doaj   +1 more source