Results 41 to 50 of about 374,450 (357)

Experimental Study on the Damage of Artificial Fracture Permeability in Coal during the Flow Back of Guar-Based Fracturing Fluid

open access: yesGeofluids, 2020
After the completion of fracturing operation in coalbed methane (CBM), the fracturing fluid needs to flow back to the ground in time to reduce the damage to the coal reservoir.
Shenggui Liu   +5 more
doaj   +1 more source

The Effect of Dynamic Fracture Strain on the Structural Response of Ships in Collisions

open access: yesJournal of Marine Science and Engineering, 2022
As ship collisions and grounding accidents lead to human injury and damage to the environment and property, more accurate predictions of structural damage to ships under impact loads are needed.
Sang Jin Kim, Jung Min Sohn
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Progressive damage and rupture in polymers

open access: yes, 2017
Progressive damage, which eventually leads to failure, is ubiquitous in biological and synthetic polymers. The simplest case to consider is that of elastomeric materials, which can undergo large reversible deformations with negligible rate dependence. In
Anand, Lallit   +2 more
core   +1 more source

Influence of the notch-sharpening technique on styrene-acrylonitrile fracture behavior [PDF]

open access: yes, 2016
The Centre Catala del Plastic and Universidad Rey Juan Carlos laboratories joined forces to investigate the effect of the notch-sharpening technique on the fracture parameters of styrene-acrylonitrile.
Illescas Fernandez, Silvia   +4 more
core   +2 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Experimental study of fracture dynamic evolution process of grouted specimen under uniaxial compression based on CT scanning

open access: yesRock and Soil Mechanics, 2022
To study the fracture dynamic evolution process of grouted specimens under loading conditions, the graded gravel grouted specimen was periodically scanned during the uniaxial compression damage process using a CT scanning system.
ZHU Chang-xing   +2 more
doaj   +1 more source

Analysis of damage and fracture formulations in cold extrusion [PDF]

open access: yes, 2017
In forming processes, components generally undergo large deformations. This induces the evolution of damage, which can influence material and product properties.
Clausmeyer, Till   +2 more
core  

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