Results 101 to 110 of about 95,238 (284)
A vascularized bone-on-a-chip model development via exploring mechanical stimulation for evaluation of fracture healing therapeutics [PDF]
, 2021 Bodhisatwa Das +5 more
openalex +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.The integration of photovoltaic (PV) systems into building structures introduces distinct fire risks with critical implications for occupant safety. This review examines the key fire hazards associated with PV implementation and explores mitigation strategies, including flame‐retardant additives.
Florian Ollagnon +7 more
wiley +1 more source
Canadian journal of surgery. Journal canadien de chirurgie, 1975 The sequence of events occurring after fracture is now relatively well understood. Healing takes place in three phases--inflammatory, reparative and remodelling. In each phase certain cells predominate and specific histologic and biochemical events are characteristic.
R L, Cruess, J, Dumont
openaire +1 more source
Osteoimmunology of Fracture Healing
Current Osteoporosis ReportsAbstract Purpose of Review The purpose of this review is to summarize what is known in the literature about the role inflammation plays during bone fracture healing. Bone fracture healing progresses through four distinct yet overlapping phases: formation of the hematoma, development of the cartilaginous callus ...
Molitoris, Kristin Happ +2 more
openaire +2 more sources
Clinical and Experimental Studies on Primary Fracture Healing (The 1st Report)
, 1971 W. Hoshiko +7 more
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Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Advanced Functional Materials, EarlyView.Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
Targeting senescent cells to boost bone fracture healing
The Journal of Clinical InvestigationBone fracture healing is a complex process with distinct phases: the inflammatory phase, the soft and hard callus formation, and the remodeling phase. In older individuals, bone healing can be delayed or disturbed, leading to non-union fractures at worst.
Lorenz C. Hofbauer +2 more
doaj +1 more source
A mathematical framework to study the mechanical and cellular activity in regulating the fracture healing process [PDF]
Xingxing Zhang +4 more
openalex +1 more source