Results 101 to 110 of about 1,770,950 (407)

Generation of Open Metatarsal Fracture in Rats: A Model for Secondary Fracture Healing

SciMedicine Journal, 2020
A fracture model in rats for the study of secondary bone healing was described. Standard open midshaft transverse metatarsal fracture was produced with bone cutting forceps in 28 rats.
Adamu Abdul Abubakar, Ahmed Khalaf Ali, Sahar Mohammed Ibrahim, Kareem Obayes Handool, Mohammad Shuaib Khan, Mustapha Mohammed Noordin, Tengku-Azmi Tengku Ibrahim, Ubedullah Kaka, Mohamad Yusof Loqman   +8 more
doaj   +1 more source

Vibration therapy as an intervention for enhancing trochanteric hip fracture healing in elderly patients: a randomized double-blinded, placebo-controlled clinical trial

Trials, 2021
Background There are more than 300,000 hip fractures yearly in the USA with mortality rates of 20% within 1 year. The treatment of osteoporotic fractures is a major challenge as bone quality is poor, and healing is expected to delay due to the impaired ...
Ronald Man Yeung Wong, Simon Kwoon Ho Chow, Ning Tang, Yik Lok Chung, James Griffith, Wing Hong Liu, Raymond Wai Kit Ng, Chi Yin Tso, Wing Hoi Cheung   +8 more
doaj   +1 more source

Age-related changes to macrophage subpopulations and TREM2 dysregulation characterize attenuated fracture healing in old mice. [PDF]

Fracture healing complications increase with age, with higher rates of delayed unions and nonunions and an associated increase in morbidity and mortality in older adults.
Brazina, Sloane, Clark, Daniel, Hsieh, Christine, Marcucio, Ralph, Miclau, Ted, Nakamura, Mary, Park, Sangmin   +6 more
core   +1 more source

The crucial role of neutrophil granulocytes in bone fracture healing.

European Cells & Materials, 2016
Delayed bone fracture healing and the formation of non-unions represent an important clinical problem, particularly in polytrauma patients who suffer from posttraumatic systemic inflammation.
A. Kovtun, Stephanie Bergdolt, R. Wiegner, P. Radermacher, Markus Huber-Lang, Anita Ignatius   +5 more
semanticscholar   +1 more source

Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan, Shravni Deshmukh, Mark Cummings, Aditi Doshi, Kourosh Rezania, Sally Freels, Gina Sawa   +6 more
wiley   +1 more source

The local and systemic effects of immune function on fracture healing

OTA International
. The immune system plays an integral role in the regulation of cellular processes responsible for fracture healing. Local and systemic influences on fracture healing correlate in many ways with fracture-related outcomes, including soft tissue healing ...
Andrew R. Evans, MD, Peter V. Giannoudis, BSc, MD, PhD, FRCS, FACS, Philip Leucht, MD, Todd O. McKinley, MD, Greg E. Gaski, MD, Katherine P. Frey, PhD, RN, Joseph C. Wenke, MD, Christopher Lee, MD   +7 more
doaj   +1 more source

Dynamization of the plate in treating nonunion of the tibial fracture: Case report

Journal of Orthopaedic Reports, 2023
Background: Plate osteosynthesis for the tibial fracture is one of the alternative treatments with satisfactory outcomes. Appropriate surgical techniques, including an open or minimally invasive approach, absolute or relative stability regarding fracture
Chittawee Jiamton, Pongsakorn Rungchamrussopa, Pariwat Taweekitikul, Techit Leelasestaporn, Theerachai Apivatthakakul   +4 more
doaj  

Incidence of and Risk of Mortality After Hip Fractures in Rheumatoid Arthritis Relative to the General Population

Arthritis Care &Research, EarlyView.
Objective Osteoporosis, a known complication of rheumatoid arthritis (RA), increases the risk of hip fracture, which is associated with high morbidity and mortality. Fracture risk estimates in patients with RA treated with contemporary treatment strategies are lacking.
C. Allyson Jones, Pierre Guy, Hui Xie, Eric C. Sayre, Kai Zhao, Diane Lacaille   +5 more
wiley   +1 more source

Association of Changes in Hand Pain With BMI, Employment, and Mental Well‐Being Over Four Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to characterize patients with hand osteoarthritis (OA) with deteriorating or improving hand pain and to investigate patients achieving good clinical outcome after four years. Methods We used four‐year annual Australian/Canadian Hand Osteoarthritis Index (AUSCAN) pain subscale (range 0–20) measurements from the Hand OSTeoArthritis in ...
Coen van der Meulen, Lotte A. van de Stadt, Saskia J. Buck, Frits R. Rosendaal, Sietse E. S. Terpstra, Margreet Kloppenburg   +5 more
wiley   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source