Macrophages—bone marrow mesenchymal stem cells crosstalk in bone healing
Frontiers in Cell and Developmental Biology, 2023 Bone healing is associated with many orthopedic conditions, including fractures and osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle-associated osteolysis.
Siyu Fan +10 more
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Bone fracture healing in mechanobiological modeling: A review of principles and methods
Bone Reports, 2017 Bone fracture is a very common body injury. The healing process is physiologically complex, involving both biological and mechanical aspects. Following a fracture, cell migration, cell/tissue differentiation, tissue synthesis, and cytokine and growth ...
Mohammad S. Ghiasi +4 more
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Effects of melatonin and vitamin E on bone healing following alloplastic grafting in osteoporotic cranial bone defects: an experimental study [PDF]
BMC Oral HealthBackground Bone healing in osteoporotic bone represents a significant clinical challenge in oral and maxillofacial surgery. The aim of this experimental study was to evaluate the effects of melatonin and vitamin E supplementation on bone healing ...
Nur Efşan Aydın, Sedat Çetiner
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Impaired bone healing upon neutrophil-specific adrenoreceptor beta 2 knockout in non-osteoporotic and osteoporotic mice [PDF]
npj Regenerative MedicineAfter a bone fracture, osteoporotic mice show delayed healing associated with elevated systemic inflammation and increased neutrophil numbers in the early fracture hematoma.
Sandra Dieterich +8 more
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Journal of Functional Biomaterials, 2022 The tendon-to-bone interface is a special structure connecting the tendon and bone and is crucial for mechanical load transfer between dissimilar tissues.
Haihan Gao +11 more
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Frontiers in Bioengineering and Biotechnology, 2023 At present, anterior cruciate ligament (ACL) reconstruction still has a high failure rate. Tendon graft and bone tunnel surface angiogenesis and bony ingrowth are the main physiological processes of tendon-bone healing, and also the main reasons for the ...
Bin Tian, Ming Zhang, Xin Kang
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Challenges to Improve Bone Healing Under Diabetic Conditions
Frontiers in Endocrinology, 2022 Diabetes mellitus (DM) can affect bone metabolism and the bone microenvironment, resulting in impaired bone healing. The mechanisms include oxidative stress, inflammation, the production of advanced glycation end products (AGEs), etc.
Yiling Chen +4 more
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Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS isoforms [PDF]
Journal of Applied Oral Science, 2023 Inducible nitric oxide synthase (iNOS) is one of the enzymes responsible for the synthesis of nitric oxide (NO), which is an important signaling molecule with effects on blood vessels, leukocytes, and bone cells.
Carolina Fávaro FRANCISCONI +9 more
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Intramembranous bone healing process subsequent to tooth extraction in mice: micro-computed tomography, histomorphometric and molecular characterization. [PDF]
PLoS ONE, 2015 Bone tissue has a significant potential for healing, which involves a significant the interplay between bone and immune cells. While fracture healing represents a useful model to investigate endochondral bone healing, intramembranous bone healing models ...
Andreia Espindola Vieira +9 more
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Journal of Nanobiotechnology, 2021 Background Rotator cuff tear (RCT) is a common problem of the musculoskeletal system. With the advantage of promoting bone formation, calcium phosphate materials have been widely used to augment tendon-bone healing.
Haoran Liao +7 more
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