Results 161 to 170 of about 1,721,489 (338)
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen+9 more
wiley +1 more source
Low-Intensity Pulsed Ultrasound Accelerates Rat Femoral Fracture Healing by Acting on the Various Cellular Reactions in the Fracture Callus [PDF]
Yoshiaki Azuma+5 more
openalex +1 more source
This work develops an ultrarobust, flexible, and solvent‐free eutectic gel featuring stretch‐induced orientation. Overcoming hydrogel limitations, the gel achieves record toughness (133.86 MJ m−3) while integrating strain/temperature/capacitive sensing.
Tingzhong Li+5 more
wiley +1 more source
Accelerated Up-Regulation of L-Sox5, Sox6, and Sox9 by BMP-2 Gene Transfer During Murine Fracture Healing [PDF]
Hannele Uusitalo+7 more
openalex +1 more source
A novel solid polymer electrolyte (SPE) to overcome interface instability in high‐energy‐density lithium metal batteries has been developed. By enhancing ionic conductivity, mechanical elasticity, and adhesion strength through all‐material UV‐crosslinking, the SPE ensures uniform lithium‐ion flow and stable performance—even after bending or cutting ...
Sung Yeon Bae+7 more
wiley +1 more source
Scaphoid blood flow and acute fracture healing [PDF]
James S Dawson+2 more
openalex +1 more source
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer+7 more
wiley +1 more source
Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño+5 more
wiley +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt+2 more
wiley +1 more source