Results 51 to 60 of about 184,235 (192)

Is sonic Hedgehog involved in human fracture healing? --a prospective study on local and systemic concentrations of SHH. [PDF]

PLoS ONE, 2014
INTRODUCTION: Sonic Hedgehog (SHH) is a new signalling pathway in bone repair. Evidence exist that SHH pathway plays a significant role in vasculogenesis and limb development during embryogenesis.
Stefan Eipeldauer, Anita Thomas, Leonard Hoechtl-Lee, Mathias Kecht, Harald Binder, Julia Koettstorfer, Markus Gregori, Kambiz Sarahrudi   +7 more
doaj   +1 more source

Long-term continuous instrumented insole-based gait analyses in daily life have advantages over longitudinal gait analyses in the lab to monitor healing of tibial fractures

Frontiers in Bioengineering and Biotechnology
Introduction: Monitoring changes in gait during rehabilitation allows early detection of complications. Laboratory-based gait analyses proved valuable for longitudinal monitoring of lower leg fracture healing.
Elke Warmerdam, Christian Wolff, Marcel Orth, Tim Pohlemann, Bergita Ganse, Bergita Ganse   +5 more
doaj   +1 more source

From Brittle to Ductile Fracture in Disordered Materials [PDF]

, 2010
We introduce a lattice model able to describe damage and yielding in heterogeneous materials ranging from brittle to ductile ones. Ductile fracture surfaces, obtained when the system breaks once the strain is completely localized, are shown to correspond
Clara B. Picallo, Juan M. López, M. Buehler, Mikko J. Alava, Stefano Zapperi   +4 more
core   +3 more sources

Impaired patient-reported outcomes but preserved gait patterns 5–15 years after acetabular fracture compared with healthy controls

Frontiers in Bioengineering and Biotechnology
IntroductionLittle is known about the long-term subjective patient experience after acetabular fracture and its relationship with changes in gait patterns.
Selma Fensel-Merz, Elke Warmerdam, Marcel Orth, Tim Pohlemann, Emmanouil Liodakis, Bergita Ganse   +5 more
doaj   +1 more source

Intact Glucocorticoid Receptor Dimerization Is Deleterious in Trauma-Induced Impaired Fracture Healing

Frontiers in Immunology, 2021
Following severe trauma, fracture healing is impaired because of overwhelming systemic and local inflammation. Glucocorticoids (GCs), acting via the glucocorticoid receptor (GR), influence fracture healing by modulating the trauma-induced immune response.
Yasmine Hachemi, Anna E. Rapp, Sooyeon Lee, Ann-Kristin Dorn, Benjamin T. Krüger, Kathrin Kaiser, Anita Ignatius, Jan Tuckermann   +7 more
doaj   +1 more source

EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing: a NICE medical technology guidance [PDF]

, 2014
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are ...
Ailish Higgins, B Campbell, B Livani, C Rubin, Catherine Meads, D Gebauer, E Mayr, I Willits, J White, Joanne Lord, K Withers, LJ Donaldson, M Schofer, M Taylor, Matthew Glover, PA Nolte, S Jingushi, S Rutten, Susan Bayliss, Yaling Yang   +19 more
core   +1 more source

Gait analysis with smart insoles can identify patients at risk of tibial shaft fracture nonunion as early as six weeks after surgery: longitudinal and cross-sectional study

Frontiers in Bioengineering and Biotechnology
BackgroundNonunion, a common and detrimental complication of tibial shaft fractures, is usually diagnosed via X-ray-based imaging. Unfortunately, it often takes months of observation until the indication for revision surgery or other interventions is ...
Elke Warmerdam, Marcel Orth, Max Müller, Tim Pohlemann, Bergita Ganse, Bergita Ganse   +5 more
doaj   +1 more source

Effectiveness of Teriparatide on Fracture Healing: A Systematic Review and Meta-Analysis.

PLoS ONE, 2016
PurposeNowadays, the efficacy of teriparatide in treating osteoporosis was widely accepted, but the discussion about using teriparatide to enhance fracture healing hasn't come to an agreement.
Zhongju Shi, Hengxing Zhou, Bin Pan, Lu Lu, Jun Liu, Yi Kang, Xue Yao, Shiqing Feng   +7 more
doaj   +1 more source

Delayed Union of a Diaphyseal Forearm Fracture Associated With Impaired Osteogenic Differentiation of Prospectively Isolated Human Skeletal Stem Cells

JBMR Plus, 2020
Delayed union or nonunion are relatively rare complications after fracture surgery, but when they do occur, they can result in substantial morbidity for the patient.
L Henry Goodnough, Thomas H Ambrosi, Holly Steininger, Malcolm R DeBaun, Geoffrey D Abrams, Timothy R McAdams, Michael J Gardner, Charles KF Chan, Julius A Bishop   +8 more
doaj   +1 more source

Timing of osteoporosis therapies following fracture: the current status

Therapeutic Advances in Endocrinology and Metabolism, 2022
In most patients, osteoporosis is diagnosed only after the occurrence of the first fragility fracture. It is of utmost importance to start osteoporosis medications immediately in these patients to prevent future fractures and also to reduce associated ...
Rajan Palui, Harsh Durgia, Jayaprakash Sahoo, Dukhabandhu Naik, Sadishkumar Kamalanathan   +4 more
doaj   +1 more source