Results 111 to 120 of about 3,200,705 (362)

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Bone cements in depressed frontal bone fractures

Annals of Maxillofacial Surgery, 2019
Skull fractures can be classified into four major types; linear, depressed, diastatic, and basilar. Of these, a depressed skull fracture presents a high risk of increased intracranial pressure or hemorrhage to the brain. A compound depressed skull fracture results when a laceration over the fracture exposes the internal cranial cavity to the outside ...
Meyyappan, Alagappan, Jagdish, Eswari, Jeevitha, Jessica Yolanda   +2 more
openaire   +3 more sources

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Risk factor identification and prevention of osteoporosis in the primary care setting [PDF]

, 2006
On one of her visits, MB Borg, a 54 year old lady, showed concern about her risk of developing osteoporosis. Lately, she had been listening to a series of radio and TV programmes on this matter where particular emphasis was put on bone density scans. She
De Gabriele, Patricia
core  

Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis. [PDF]

, 2020
The surgeon general of the USA defines osteoporosis as "a skeletal disorder characterized by compromised bone strength, predisposing to an increased risk of fracture." Measuring bone strength, Biomechanical Computed Tomography analysis (BCT), namely ...
Bouxsein, ML, Clarke, BL, Cosman, F, Keaveny, TM, Khosla, S, Orwoll, ES, Siris, ES   +6 more
core  

Tough, Ductile, and Strong Hard‐Soft Cementitious Composite Enabled by Multi‐Material Additive Manufacturing

Advanced Materials, EarlyView.
Drawing inspiration from the layered hard‐soft architecture found in sea sponges, this work establishes a new framework for architected cementitious composites (ACC) through multi‐material additive manufacturing (MMAM) process. The integration of mortar and elastomer phases into layered architectures enables synergistic toughening mechanisms, including
Aimane Najmeddine, Shashank Gupta, William Makinen, Zayvinn Lin, Krystal Delnoce, Reza Moini   +5 more
wiley   +1 more source

Influence of trabecular microstructure and cortical index on the complexity of proximal humeral fractures [PDF]

, 2018
Objectives: Poor bone quality increases the susceptibility to fractures of the proximal humerus. It is unclear whether local trabecular and cortical measures influence the severity of fracture patterns.
Diederichs, Gerd, Hepp, Pierre, Josten, Christoph, Osterhoff, Georg, Tami, Andrea, Theopold, Jan   +5 more
core  

Comorbidities only account for a small proportion of excess mortality after fracture: A record linkage study of individual fracture types [PDF]

, 2018
Background: Non-hip non-vertebral fractures (NHNV) constitute the majority of osteoporotic fractures but few studies have examined the association between these fractures, co-morbidity and mortality.
Bliuc, Dana, Blyth, Fiona, Center, Jacqueline, Eisman, John A, March, Lynette, Nguyen, Tuan, Simpson, Judy, Tran, Thach, Weiwen, Chen   +8 more
core   +2 more sources

Pseudotumoral Calcinosis Following Bone Fracture

Journal of the Belgian Society of Radiology, 2019
Pseudotumoral calcinosis could present as large heterogeneous calcified masses with fluid levels and sedimentation.
Toubeau, Arnaud, Malasi, Sokol, Sarbu, Nicolae   +2 more
openaire   +6 more sources