Results 111 to 120 of about 204,551 (269)

Strain‐Adaptive Dielectric Metamaterials via Bioinspired “Ligament‐Bone” Architecture for Ultrahigh‐Energy Capacitive Storage

Advanced Science, EarlyView.
A bioinspired strain‐adaptive ligament‐bone architecture achieves record‐high energy density of 26.1 J cm−3 and 90% efficiency at 600 MV m−1, coupled with a Young's modulus of 2.13 GPa. ABSTRACT Polymer dielectrics for capacitive energy storage face fundamental trade‐offs between breakdown strength, energy density, efficiency, and mechanical robustness.
Jian Wang, Xinyu Wang, Jiabao Wang, Biyun Peng, Yifei Zhang, Ning Zhu, Xin Hu   +6 more
wiley   +1 more source

Fractures, Bone Mineral Density, and Final Height in Craniopharyngioma Patients with a Follow-up of 16 Years.

J Clin Endocrinol Metab, 2020
van Santen SS, Olsson DS, van den Heuvel-Eibrink MM, Wijnen M, Hammarstrand C, Janssen JAMJL, Johansson G, van der Lely AJ, Neggers SJCMM.   +8 more
europepmc   +1 more source

Programmable Multi‐Axially Aligned Aerogels via Sequential Freeze‐Casting for Tailored Anisotropy and Tunable Mechanics

Advanced Science, EarlyView.
Conventional single‐gradient freeze‐casting typically produces unidirectional porous architectures with limited transverse connectivity. The Sequential Hybridization by Infiltration and Freeze‐casting Technique (SHIFT) addresses this constraint by integrating secondary aligned structures within a preformed primary scaffold.
Kiho Sung, Sungchul Shin
wiley   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

Advanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky, Emma Anisman, Ron Perez, Sophia Zhang, Morgan Hoffman, Daniel Hunter, Abigail Cherian, Jevon Bonner, Emilia Feria, Ahmed Ahmed, Muneeb Malik, Junwei Du, Leland C. Sudlow, David M. Brogan, Matthew D. Wood, Mikhail Y. Berezin   +15 more
wiley   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

Chemically Gradient Ordered Nanodomains Enable Large Tensile Ductility in Gigapascal Lightweight Refractory High‐Entropy Alloys

Advanced Science, EarlyView.
A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang, Dingshun Yan, Yong Zhang, Zhiming Li   +3 more
wiley   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source