Results 1 to 10 of about 3,133,668 (199)

Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation

open access: yesDisease Models & Mechanisms, 2020
Improving revascularization is one of the major measures in fracture treatment. Moderate local inflammation triggers angiogenesis, whereas systemic inflammation hampers angiogenesis.
Jiang-Hua Liu   +11 more
semanticscholar   +1 more source

Sonic Hedgehog Regulates Bone Fracture Healing

open access: yesInternational Journal of Molecular Sciences, 2020
Bone fracture healing involves the combination of intramembranous and endochondral ossification. It is known that Indian hedgehog (Ihh) promotes chondrogenesis during fracture healing.
H. Takebe   +4 more
semanticscholar   +1 more source

Recent advances in biodegradation controls over Mg alloys for bone fracture management: A review

open access: yesJournal of Materials Science & Technology, 2019
Magnesium (Mg) alloys possess comparable physical and mechanical properties to bone, making them an outstanding candidate of implant materials for bone fracture treatment.
M. Song   +7 more
semanticscholar   +1 more source

Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing

open access: yesScience Advances, 2020
We provide the first genetic evidence that LSD1 in skeletal cells is critical for endochondral ossification during bone repair. Bone fracture is repaired predominantly through endochondral ossification.
Jun Sun   +9 more
semanticscholar   +1 more source

Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Our results show that one single systemic administration of the β-adrenoreceptor blocker propranolol prior to femur osteotomy in psychosocially stressed mice prevents stress-induced bone marrow mobilization of neutrophils and their ...
M. Haffner-Luntzer   +10 more
semanticscholar   +1 more source

Bone fracture healing: perspectives according to molecular basis

open access: yesJournal of Bone and Mineral Metabolism, 2020
Fractures have a great impact on health all around the world and with fracture healing optimization; this problem could be resolved partially. To make a practical contribution to this issue, the knowledge of bone tissue, cellularity, and metabolism is ...
I. N. Camal Ruggieri   +3 more
semanticscholar   +1 more source

Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats

open access: yesNature Medicine, 2016
Orthopedic implants containing biodegradable magnesium have been used for fracture repair with considerable efficacy; however, the underlying mechanisms by which these implants improve fracture healing remain elusive.
Yi-Feng Zhang   +27 more
semanticscholar   +1 more source

Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing

open access: yesInternational Journal of Molecular Sciences, 2019
Pericytes are mesenchymal cells that surround the endothelial cells of small vessels in various organs. These cells express several markers, such as NG2, CD146, and PDGFRβ, and play an important role in the stabilization and maturation of blood vessels ...
S. Supakul   +12 more
semanticscholar   +1 more source

Bone fracture healing in mechanobiological modeling: A review of principles and methods

open access: yesBone Reports, 2017
Bone fracture is a very common body injury. The healing process is physiologically complex, involving both biological and mechanical aspects. Following a fracture, cell migration, cell/tissue differentiation, tissue synthesis, and cytokine and growth ...
M. S. Ghiasi   +4 more
semanticscholar   +1 more source

Carpal Bone Fracture

open access: yesDefinitions, 2020
This datasheet on carpal bone fracture covers Identity, Hosts/Species Affected, Diagnosis.

semanticscholar   +1 more source

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