Results 21 to 30 of about 3,122,739 (367)

Skeletal Fragility in Type 2 Diabetes Mellitus [PDF]

Endocrinology and Metabolism, 2018
Type 2 diabetes (T2D) is associated with an increased risk of fracture, which has been reported in several epidemiological studies. However, bone mineral density in T2D is increased and underestimates the fracture risk.
Jakob Starup-Linde, Katrine Hygum, Bente Lomholt Langdahl   +2 more
doaj   +1 more source

DO OLDER PATIENTS “WARN” THAT THEY WILL SUFFER A NEW FRACTURE? [PDF]

Acta Ortopédica Brasileira, 2023
Objective: To evaluate whether patients older than 60 years admitted for fracture treatment had a history of previous fracture, a diagnosis of osteoporosis, or were under treatment for bone fragility.
SAMUEL BICHARA MELIN, MARCELA RODRIGUES SANTOS DO NASCIMENTO, ALFREDO DOS SANTOS NETTO, CAIO ZAMBONI   +3 more
doaj   +1 more source

Impairment of cold injury-induced muscle regeneration in mice receiving a combination of bone fracture and alendronate treatment. [PDF]

PLoS ONE, 2017
Alendronate, a nitrogen-containing bisphosphonate, is well established as a treatment for osteoporosis through regulation of osteoclast activity. Previously, the pharmacological effects of bisphosphonates on cells outside the bone environment have been ...
Shigeo Kawada, Atsushi Harada, Naohiro Hashimoto   +2 more
doaj   +1 more source

Single-Cell RNA Sequencing Reveals B Cells Are Important Regulators in Fracture Healing

Frontiers in Endocrinology, 2021
The bone marrow microenvironment is composed primarily of immune and stromal cells that play important roles in fracture healing. Although immune cells have been identified in mouse bone marrow, variations in their numbers and type during the fracture ...
Hao Zhang, Renkai Wang, Renkai Wang, Guangchao Wang, Bo Zhang, Chao Wang, Di Li, Chen Ding, Qiang Wei, Zhenyu Fan, Hao Tang, Fang Ji, Fang Ji   +12 more
doaj   +1 more source

Risk factors of fracture following curettage for bone giant cell tumors of the extremities

BMC Musculoskeletal Disorders, 2022
Background Following curettage of giant cell tumor of bone (GCTB), it is common to fill the cavity with polymethylmethacrylate (PMMA) bone cement, bone allograft, or artificial bone to maintain bone strength; however, there is a 2–14% risk of ...
Shinji Tsukamoto, Andreas F. Mavrogenis, Manabu Akahane, Kanya Honoki, Akira Kido, Yasuhito Tanaka, Davide Maria Donati, Costantino Errani   +7 more
doaj   +1 more source

Quantitative Ultrasound of Cortical Bone in the Femoral Neck Predicts Femur Strength: Results of a Pilot Study [PDF]

, 2013
Article first published online: 15 JAN 2013 Pour consulter la version éditeur DOI: 10.1002/jbmr.1742A significant risk of femoral neck (FN) fracture exists for men and women with an areal bone mineral density (aBMD) higher than the osteoporotic range ...
GRONDIN, Julien, ENGELKE, Klaus, Reinhard Barkmann, GRIMAL, Quentin, Quentin Grimal, Sandra Guérard, Glüer, Claus-C., Julien Grondin, GUÉRARD, Sandra, Klaus Engelke, GLÜER, Claus-C, BARKMANN, Reinhard, Claus‐C Glüer, Pascal Laugier, LAUGIER, Pascal   +14 more
core   +1 more source

Bone fractures after menopause [PDF]

, 2010
Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength.PubMed searches were performed, for studies of the ...
Ralston, Stuart H., J. L. Evers, Baird, D. T., A. Volpe, Ralston, S.H., Brandi, M.L., G. Benagiano, Brandi, Maria Luisa, S. H. Ralston, P.G. Crosignani, P. Bouchard, Rizzoli, R., ESHRE Capri Workshop Grp, Barlow, David H., La Vecchia, C., Negri, E., M. L. Brandi, P. G. Crosignani, Rizzoli, Rene, Benagiano, G., S. E. Papapoulos, Evers, J.L.H., D. H. Barlow, J. Collins, C. La Vecchia, Baird, D.T., Negri, Eva, Crosignani, P. G., Papapoulos, Socrates E., Glasier, A., R. Rizzoli, Barlow, D.H., A. Glasier, Vecchia, C. la, Collins, J., D. T. Baird, Volpe, A., Bouchard, P., Crosignani, P.G., Bouchard, Philippe, ?, ?, Papapoulos, S.E., E. Negri, Evers, J. L. H.   +43 more
core   +1 more source

A retrospective clinical investigation for the effectiveness of closed reduction on nasal bone fracture

Maxillofacial Plastic and Reconstructive Surgery, 2019
Background The nasal bone is the most protruding bony structure of the facial bones. Nasal bone fracture is the most common facial bone fracture. The high rate of incidence of nasal bone fracture emphasizes the need for systematical investigation of ...
Byung-Hun Kang, Hyo-Sun Kang, Jeong Joon Han, Seunggon Jung, Hong-Ju Park, Hee-Kyun Oh, Min-Suk Kook   +6 more
doaj   +1 more source

RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes [PDF]

, 2015
Context: The RANK/RANKL/OPG signalling pathway is important in the regulation of bone turnover, with single nucleotide polymorphisms (SNPs) in genes within this pathway associated with bone phenotypic adaptations.
Stellingwerff, Trent, Varley, Ian, Sale, C, Ranson, Craig, Greeves, JP, Ranson, C, Fraser, WD, Stellingwerff, T, Hughes, David C, Varley, I, Greeves, Julie P, Sale, Craig, Hughes, DC, Fraser, William D   +13 more
core   +1 more source

Exosomal miRNA-128-3p from mesenchymal stem cells of aged rats regulates osteogenesis and bone fracture healing by targeting Smad5

Journal of Nanobiotechnology, 2020
Transplantation of mesenchymal stem cells (MSCs) has been considered an effective therapeutic treatment for a variety of diseases including bone fracture. However, there are associated complications along with MSCs transplantation.
Tao Xu, Yongjun Luo, Jiaxing Wang, Ning Zhang, Changjiang Gu, Linwei Li, Dingfei Qian, Weihua Cai, Jin Fan, G. Yin   +9 more
semanticscholar   +1 more source