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Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting bone tissue and leading to increased fracture risk in men and women, independent of bone mineral density (BMD).
Eva M. Wölfel +14 more
doaj +1 more source
Use of depot medroxyprogesterone acetate and fracture risk [PDF]
Depot medroxyprogesterone acetate (DMPA), which has a high rate of use among teenagers in Europe and the United States, has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life.
Kraenzlin, Marius E. +9 more
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BackgroundThe incidence of distal forearm fracture due to minimal/moderate trauma shows a bimodal distribution for age at event, with one peak occurring during early adolescence, in both boys and girls and the other one in postmenopausal females. The aim
Velimir Matkovic +7 more
doaj +1 more source
The Warwick Hip Trauma Evaluation – an abridged protocol for the WHiTE Study : a multiple embedded randomised controlled trial cohort study [PDF]
Fractures of the proximal femur are one of the greatest challenges facing the medical community, constituting a heavy socioeconomic burden worldwide. The National Hip Fracture Audit currently provides a framework for service evaluation.
Griffin, Xavier L. +11 more
core +1 more source
An approximate model for cancellous bone screw fixation [PDF]
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Taylor & Francis.This paper presents a finite element (FE) model to identify parameters that affect the performance of an improved ...
Brown, CJ +9 more
core +1 more source
Background: Osteosarcopenia is a syndrome coexisting sarcopenia and osteopenia/osteoporosis, with a high fracture risk. Recently, skeletal muscle and bone have been recognized as endocrine organs capable of communication through secreting myokines and ...
Renwang Sheng +9 more
doaj +1 more source
Bone disease is a serious complication to diabetes. Patients with type 1 diabetes (T1D) and type 2 diabetes (T2D) suffer from an increased risk of fracture, most notably at the hip, compared with patients without diabetes. Confounders such as patient sex,
Katrine Hygum +2 more
doaj +1 more source
Effects of osteoporosis and drugs on bone biomechanics. [PDF]
PhD16 New Zealand White (NZW) rabbits were ovariectomised (OVX) and 20 left intact as age-matched controls. 4 controls were killed at time 0, then 4 from each group at 1,3,6 and 12 months post-OVX. Serum oestradiol and body weight were recorded.
Bagnall, Anne-Marie
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Cortical bone is a transversely isotropic material, and the mechanical properties may be related to the loading direction on the osteon. Therefore, analyzing the differences in the failure processes of cortical bone under different loading conditions is ...
Xiaofeng Dai +3 more
doaj +1 more source
Development of Patient-Specific CT-FE Modelling of Bone Through Validation Using Porcine Femora [PDF]
A&E statistics in the UK demonstrate that as high as 60% of bone fractures occur as a result of trips and falls. Subsequently, many studies have been undertaken to simulate the occurrence of hip fractures. Little simulation has been considered outside of
Emerson, Nicholas
core +6 more sources

