Results 141 to 150 of about 503,381 (321)

Gene Expression Profiles in a Transgenic Animal Model of Fragile X Syndrome

, 2002
Velia D’Agata, Stephen T. Warren, Weiqin Zhao, Enrique Torre, Daniel L. Alkon, Sebastiano Cavallaro   +5 more
openalex   +2 more sources

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Negative effect of treatment with mGluR5 negative allosteric modulator AFQ056 on blood biomarkers in young individuals with Fragile X syndrome

SAGE Open Medicine
Background: Fragile X syndrome, with an approximate incidence rate of 1 in 4000 males to 1 in 8000 females, is the most prevalent genetic cause of heritable intellectual disability and the most common monogenic cause of autism spectrum disorder. The full
Dragana Protic, Elizabeth Breeze, Guadalupe Mendoza, Marwa Zafarullah, Leonard Abbeduto, Randi Hagerman, Christopher Coffey, Merit Cudkowicz, Blythe Durbin-Johnson, Paul Ashwood, Elizabeth Berry-Kravis, Craig A Erickson, Robin Filipink, Andrea Gropman, Lenora Lehwald, Angela Maxwell-Horn, Stephanie Morris, Amanda Palladino Bennett, Lisa Prock, Amy Talboy, Nicole Tartaglia, Jeremy Veenstra-VanderWeele, Flora Tassone   +22 more
doaj   +1 more source

Fragile States: A Case Study Exploring Genetics, Molecular Biology, and Biochemistry Through the Lens of Fragile X Syndrome

, 2023
Amy T. Hark, Lauren E. Washco
openalex   +2 more sources

Hydrogel‐Based Vat Photopolymerization of Ceramics and Metals with Low Shrinkages via Repeated Infusion Precipitation

Advanced Materials, EarlyView.
This work introduces an in situ precipitation strategy for the hydrogel‐based vat photopolymerization of architected ceramics and metals with reduced shrinkages and improved densities. Repeated infusion‐precipitation significantly increases metal loading within the hydrogels, which improves part quality after thermal conversion.
Yiming Ji, Ying Hong, Dhruv R. Bhandari, Daryl W. Yee   +3 more
wiley   +1 more source

COMPREHENSIVE TRANSCRIPTOME-BASED DRUG REPOSITIONING FOR FRAGILE X SYNDROME [PDF]

, 2023
Sejin Jeon, Chan Young Shin, Yujeong Kim, TaeJin Ahn   +3 more
openalex   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Attitudes toward prenatal screening and testing for Fragile X [PDF]

, 2006
Joanna H. Fanos, Kerstin A Spangner, Thomas J. Musci   +2 more
openalex   +1 more source

Correction: Differential regulation of BK channels by fragile X mental retardation protein [PDF]

, 2020
Aravind Kshatri, Alejandro Cerrada, Roger Gimeno, David Bartolomé‐Martín, Patricio Rojas, Teresa Giráldez   +5 more
openalex   +1 more source