Results 271 to 280 of about 503,381 (321)

A case of fragile X-associated tremor/ataxia syndrome with superior cerebellar peduncle lesions. [PDF]

eNeurologicalSci
Ishizawa K, Hashimoto K, Oka H, Sugawara T, Amari M, Kawarabayashi T, Okamoto K, Tamai C, Sone J, Ikeda Y, Takatama M, Shoji M.   +11 more
europepmc   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

Advanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen, Qingwei Zeng, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao   +6 more
wiley   +1 more source

Longitudinal Analysis of Neuroradiological Biomarkers for Fragile X-Associated Tremor/Ataxia Syndrome and Implications for Clinical Trials. [PDF]

Ann Neurol
Hessl D, Wang JY, Espinal G, Santos E, Tassone F, Hagerman RJ, Rivera SM.   +6 more
europepmc   +1 more source

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

Advanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun, Long Zhao, Zhen Shi, Jingting Wang, Shang Yang, Xia Qi, Hengrui Zhang, Ting Wang, Weiyun Shi   +8 more
wiley   +1 more source

Knowledge and perceptions about fragile X syndrome and fragile X-premutation-associated conditions among medical doctors in Nigeria. [PDF]

Clin Genet
Mbachu CNP, Hagerman R, Eseigbe E, Odita A, Mbachu I, Ilikanu S, Akowundu K, Ndukwu C, Echezona M, Okereke O, Echendu S, Udigwe I.   +11 more
europepmc   +1 more source

Gecko‐Inspired Adhesive for Robotic Grippers with Excellent Ultra‐Low‐Temperature Adhesion Performance

Advanced Science, EarlyView.
Phenyl and vinyl groups are used to modify conventional polydimethylsiloxane (PDMS) to yield poly(methylphenylvinylsiloxane) (PMPVS). PMPVS‐based gecko‐inspired arrays with mushroom tips exhibit superior adhesion strength of 36.7 kPa even at −80 °C, which enhances by 5143% compared to PDMS‐based arrays (0.7 kPa at −70 °C).
Jiabao Feng, Hong Zhu, Yadong Lv, Qi Yang, Guangxian Li, Miqiu Kong, Wei Pu   +6 more
wiley   +1 more source

Frontal cortex hyperactivation and gamma desynchrony in Fragile X syndrome: Correlates of auditory hypersensitivity. [PDF]

PLoS One
Pedapati EV, Ethridge LE, Liu Y, Liu R, Sweeney JA, DeStefano LA, Miyakoshi M, Razak K, Schmitt LM, Moore DR, Gilbert DL, Wu SW, Smith E, Shaffer RC, Dominick KC, Horn PS, Binder D, Erickson CA.   +17 more
europepmc   +1 more source

Miniature Robotic Swimmer with Precise 2D Motion Control via Acoustic Vortex‐Induced Propulsion

Advanced Science, EarlyView.
In this work, a miniature robotic swimmer achieves precise 2D motion using sound waves with customized 3D‐printed lenses. Localized acoustic vortices drive both translation and rotation of the swimmer without mechanical parts. This contactless approach offers a novel route to controlled micro‐scale movement, with promising applications in biomedical ...
Chadi Ellouzi, Nicholas Andrianto, Glen Vosgerichian, Farhood Aghdasi, Joshua Lloyd, Ali Zabihi, Chen Shen   +6 more
wiley   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source