Results 311 to 320 of about 5,538,805 (353)

A Phase 3 Multicenter, Double‐Blind Study Comparing Efficacy, Safety, Immunogenicity, and Pharmacokinetics of Alkem's Biosimilar Teriparatide Versus Reference Teriparatide in Postmenopausal Osteoporosis

AGING MEDICINE, EarlyView.
This phase III study demonstrated that Alkem's biosimilar teriparatide is noninferior to reference teriparatide in improving bone mineral density at the lumbar spine and femoral neck in postmenopausal osteoporosis patients, with comparable safety, pharmacodynamics, and immunogenicity profiles over 48 weeks of treatment.
Nitin Kapoor, Thomas Paul, Rajeshwar Nath Srivastava, Saurabh Singh, Sunil Maheshwari, Vishal Patil, Awadhesh Kumar Yadav, Girish Bhatia, Sushil H. Mankar, Joe Joseph Cherian, Surabhi Maheshwari, Sudeepti Srivastava, Dattatray Pawar, Roshan Pawar, Amol Aiwale, Amitrajit Pal, Yogesh Rane, Vinayaka Shahavi, Akhilesh Sharma   +18 more
wiley   +1 more source

Nigrostriatal Degeneration Underpins Sensorimotor Dysfunction in an Inducible Mouse Model of Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS). [PDF]

Int J Mol Sci
Kul E, Santos M, Stork O.
europepmc   +1 more source

Cell- and Pathway-Specific Disruptions in the Accumbens of Fragile X Mouse. [PDF]

J Neurosci
Giua G, Pereira-Silva J, Caceres-Rodriguez A, Lassalle O, Chavis P, Manzoni OJ.   +5 more
europepmc   +1 more source

Establishment of a Nonradioactive Molecular Diagnosis of Fragile-X Syndrome

, 2000
Zehra Oya Uyguner, Bernd Wollnik, Hülya Kayserili, Turgut Tükel, Seher Başaran, Memnune Yüksel Apak   +5 more
openalex  

Somatic Instability Leading to Mosaicism in Fragile X Syndrome and Associated Disorders: Complex Mechanisms, Diagnostics, and Clinical Relevance. [PDF]

Int J Mol Sci
Protic D, Polli R, Bettella E, Usdin K, Murgia A, Tassone F.   +5 more
europepmc   +1 more source

In Utero Alcohol and Unsuitable Home Environmental Exposure Combined with <i>FMR1</i> Full Mutation Allele Cause Severe Fragile X Syndrome Phenotypes. [PDF]

Int J Mol Sci
Winarni TI, Aishworiya R, Culpepper H, Zafarullah M, Mendoza G, Wilaisakditipakorn TJ, Likhitweerawong N, Law J, Hagerman R, Tassone F.   +9 more
europepmc   +1 more source

Mitochondrial dysfunction in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome: prospect use of antioxidants and mitochondrial nutrients. [PDF]

Mol Biol Rep
Pagano G, Lyakhovich A, Pallardó FV, Tiano L, Zatterale A, Trifuoggi M.   +5 more
europepmc   +1 more source

Spontaneous distal middle cerebral artery aneurysm in a young male with full mutation of the fragile X syndrome with a high-functioning phenotype: illustrative case. [PDF]

J Neurosurg Case Lessons
Papadopoulos E, Abrimian A, Zarzour H, Hagerman RJ, Schmidt RF.   +4 more
europepmc   +1 more source

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Fragile X syndrome

Nature Reviews Disease Primers, 2017
Fragile X syndrome (FXS) is the leading inherited form of intellectual disability and autism spectrum disorder, and patients can present with severe behavioural alterations, including hyperactivity, impulsivity and anxiety, in addition to poor language development and seizures.
Hagerman, Randi J., Berry-Kravis, Elizabeth, Hazlett, Heather Cody, Bailey, Donald B., Jr., Moine, Herve, Kooy, Frank, Tassone, Flora, Gantois, Ilse, Sonenberg, Nahum, Mandel, Jean Louis, Hagerman, Paul J.   +10 more
openaire   +5 more sources