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Beyond the Fragile X protein: neighborhood characteristics explain individual differences in IQ and adaptive behaviors of Fragile X syndrome. [PDF]
McKinney WS +6 more
europepmc +1 more source
Gene Therapy for Fragile X Syndrome, Challenges, and Promises. [PDF]
Velinov M.
europepmc +1 more source
FMR1 reduction alters cellular and circuit properties in human cortex
Singh A +17 more
europepmc +1 more source
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Neuroscience, 2023
The Planar cell polarity (PCP) pathway is known to mediate the function of the Wnt proteins in growth cone guidance. Here, we show that the PCP pathway may directly influence local protein synthesis within the growth cones. We found that Fragile X Messenger Ribonucleoprotein 1 (FMRP) interacts with Fzd3.
John R Yates +2 more
exaly +3 more sources
The Planar cell polarity (PCP) pathway is known to mediate the function of the Wnt proteins in growth cone guidance. Here, we show that the PCP pathway may directly influence local protein synthesis within the growth cones. We found that Fragile X Messenger Ribonucleoprotein 1 (FMRP) interacts with Fzd3.
John R Yates +2 more
exaly +3 more sources
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2023
openaire +1 more source
openaire +1 more source
Mechanisms Driving the Emergence of Neuronal Hyperexcitability in Fragile X Syndrome
International Journal of Molecular Sciences, 2022Menahem Segal +2 more
exaly

