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FMR1 reduction alters cellular and circuit properties in human cortex

open access: yes
Singh A   +17 more
europepmc   +1 more source
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The Fragile X Messenger Ribonucleoprotein 1 Participates in Axon Guidance Mediated by the Wnt/Planar Cell Polarity Pathway

Neuroscience, 2023
The Planar cell polarity (PCP) pathway is known to mediate the function of the Wnt proteins in growth cone guidance. Here, we show that the PCP pathway may directly influence local protein synthesis within the growth cones. We found that Fragile X Messenger Ribonucleoprotein 1 (FMRP) interacts with Fzd3.
John R Yates   +2 more
exaly   +3 more sources

Absence of the Fragile X messenger ribonucleoprotein alters response patterns to sounds in the auditory midbrain

Frontiers in Neuroscience, 2022
Jeremie Sibille   +2 more
exaly  

Mechanisms Driving the Emergence of Neuronal Hyperexcitability in Fragile X Syndrome

International Journal of Molecular Sciences, 2022
Menahem Segal   +2 more
exaly  

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