Results 101 to 110 of about 103,930 (219)

Glycopyrronium 320 μg/mL in children and adolescents with severe sialorrhoea and neurodisabilities: An open‐label study extension of the SALIVA trial

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16268 Abstract Aims To test the long‐term efficacy, safety, and impact on quality of life (QoL) of an oral paediatric formulation of 320 μg/mL glycopyrronium in the 36‐week SALIVA (Sialanar plus orAl rehabiLitation against placebo plus oral rehabilitation for chIldren and ...
Pierre Fayoux, Mickael Dinomais, Helen Shaw, Frédéric Villain, Déborah Schwartz, Vincent Gautheron, Guy Letellier, Stéphane Auvin   +7 more
wiley   +1 more source

Cerebral palsy and perinatal mortality in children born in Norway to immigrant mothers

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16271 Abstract Aim To compare the prevalence and clinical characteristics of cerebral palsy (CP), and perinatal mortality, in children born to non‐immigrant mothers with children born to immigrant mothers. Method This was a registry‐based cross‐sectional study.
Maria Wiedswang Sigholt, Guro L. Andersen, Stian Lydersen, Liv Cecilie Vestrheim Thomsen, Torstein Vik, Sandra Julsen Hollung   +5 more
wiley   +1 more source

Pathogenic variants in chromatin‐related genes: Linking immune dysregulation to neuroregression and acute neuropsychiatric disorders

Developmental Medicine &Child Neurology, EarlyView.
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale, Shekeeb Mohammad, Velda X. Han, Hiroya Nishida, Himanshu Goel, Stuart G. Tangye, Georgina Hollway, Esther Tantsis, Deepak Gill, Shrujna Patel, Chromatin Immune‐Brain Group, Michael Lonergan, Melanie Wong, Kavitha Kothur, Erica Tsang   +14 more
wiley   +1 more source

Deep developmental phenotyping in children with tuberous sclerosis complex, with and without autism

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16312 Abstract Aim To characterize autism and co‐occurring tuberous sclerosis‐associated neuropsychiatric disorders (TAND) in children with tuberous sclerosis complex (TSC), addressing evidence gaps by using deep developmental phenotyping in a single cohort.
Rebecca A. Mitchell, Francesca Lami, Sarah M. Barton, A. Simon Harvey, Katrina Williams   +4 more
wiley   +1 more source

Characterising equine abdominal lipomata: Can histological features improve the understanding of pathogenesis and risk?

Equine Veterinary Journal, EarlyView.
Abstract Background Strangulating lipomata are the most common cause of small intestinal strangulating obstruction. Evaluation of histological features of pathological and non‐pathological lipomata, and the histological properties of omental and retroperitoneal fat have not been described.
Alexandra Gillen, Debra Archer, Joanne Ireland, Guido Rocchigiani   +3 more
wiley   +1 more source

The Experience of Stigma in People Affected by Fibromyalgia: A Metasynthesis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To review the qualitative literature regarding how people with fibromyalgia experience and are impacted by stigma. Design A systematic review and metasynthesis of qualitative studies was conducted following the Thomas and Harden method. Methods The electronic databases PubMed, CINAHL, PsycInfo, Embase and Scopus were queried (September ...
Benedetta Colombo, Eleonora Zanella, Alessandro Galazzi, Paola Arcadi   +3 more
wiley   +1 more source

Children With Fragile X Syndrome Display a Switch Towards Fast Fibres in Their Recruitment Strategy During Gait

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Fragile X Syndrome (FXS) is a genetic disorder caused by the lack of FMRP, a crucial protein for brain development and function. FMR1 mutations are categorized into premutation and full mutation (FXSFull), with somatic mosaicism (FXSMos) modulating the FXS phenotype.
Fabiola Spolaor, Federica Beghetti, Weronika Piatkowska, Annamaria Guiotto, Roberta Polli, Elisa Bettella, Valentina Liani, Elisa di Giorgio, Zimi Sawacha   +8 more
wiley   +1 more source

Prevalence and Incidence of Cardiovascular Disease in Adults With Intellectual Disabilities: A Systematic Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Given the high risk of cardiovascular diseases (CVD) in adults with intellectual disabilities (ID), there is a strong need for accurate understanding on CVD prevalence and incidence in this population. This information is important to ensure optimal care and resource allocation. However, systematic reviews on this topic are limited.
Marleen J. de Leeuw, Thessa I. M. Hilgenkamp, Dederieke A. M. Maes‐Festen, Patrick J. E. Bindels, Roy G. Elbers, Alyt Oppewal   +5 more
wiley   +1 more source

Frontal cortex hyperactivation and gamma desynchrony in Fragile X syndrome: Correlates of auditory hypersensitivity. [PDF]

PLoS One
Pedapati EV, Ethridge LE, Liu Y, Liu R, Sweeney JA, DeStefano LA, Miyakoshi M, Razak K, Schmitt LM, Moore DR, Gilbert DL, Wu SW, Smith E, Shaffer RC, Dominick KC, Horn PS, Binder D, Erickson CA.   +17 more
europepmc   +1 more source

P3 abnormality in fragile X syndrome [PDF]

, 1987
Blackwood, D, Dickens, P, Oliver, C, St. Clair, D   +3 more
core   +1 more source