Results 131 to 140 of about 103,930 (219)

How close are we to a cAMP- and cGMP-theory-based pharmacological therapy for fragile X syndrome? [PDF]

Cell Rep Med
Bardoni B, Gwizdek C, Maurin T.
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Trinucleotide repeat expansion and RNA dysregulation in fragile X syndrome: emerging therapeutic approaches. [PDF]

RNA
Jung S, Richter JD.
europepmc   +1 more source

Managing and mitigating future public health risks: Planetary boundaries, global catastrophic risk, and inclusive wealth

Risk Analysis, EarlyView.
Abstract There are two separate conceptualizations for assessing existential risks: Planetary Boundaries (PBs) and global catastrophic risks (GCRs). While these concepts are similar in principle, their underpinning literatures tend not to engage with each other.
Eoin McLaughlin, Matthias Beck
wiley   +1 more source

Epigenetic insights into Fragile X Syndrome. [PDF]

Front Cell Dev Biol
Xie L, Li H, Xiao M, Chen N, Zang X, Liu Y, Ye H, Tang C.   +7 more
europepmc   +1 more source

RNA-binding proteins in disease etiology: fragile X syndrome and spinal muscular atrophy. [PDF]

RNA
Dreyfuss G.
europepmc   +1 more source

A near normal distribution of IQ in Fragile X Syndrome. [PDF]

Sci Rep
Schmitt LM, Nelson M, Shaffer RC, Erickson CA.   +3 more
europepmc   +1 more source

Hippocampal-prefrontal functional neural networks in a rat model of fragile X syndrome are poorly organized with limited resiliency. [PDF]

Sci Rep
Ouardouz M, Jasinski P, Khalife M, Mahoney JM, Hernan AE, Scott RC.   +5 more
europepmc   +1 more source

Adaptive functioning in children and young adults with monogenic neurodevelopmental disorders

Developmental Medicine &Child Neurology, Volume 67, Issue 7, Page 953-962, July 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16264 Abstract Aim To examine the adaptive behaviour profiles of children with monogenic neurodevelopmental disorders (NDDs) to determine whether syndrome‐specific or transdiagnostic approaches provide a better understanding of the adaptive behavioural phenotypes of these NDDs ...
Emma K. Baker, Miya St John, Ruth Braden, Lottie D. Morison, Elana J. Forbes, Fatma Lelik, Stephen J. C. Hearps, David J. Amor, Angela T. Morgan   +8 more
wiley   +1 more source

Compensatory Regulation of Excitation/Inhibition Balance in the Ventral Hippocampus: Insights from Fragile X Syndrome. [PDF]

Biology (Basel)
Papatheodoropoulos C.
europepmc   +1 more source