How close are we to a cAMP- and cGMP-theory-based pharmacological therapy for fragile X syndrome? [PDF]
Bardoni B, Gwizdek C, Maurin T.
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AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer+4 more
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Trinucleotide repeat expansion and RNA dysregulation in fragile X syndrome: emerging therapeutic approaches. [PDF]
Jung S, Richter JD.
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Abstract There are two separate conceptualizations for assessing existential risks: Planetary Boundaries (PBs) and global catastrophic risks (GCRs). While these concepts are similar in principle, their underpinning literatures tend not to engage with each other.
Eoin McLaughlin, Matthias Beck
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Epigenetic insights into Fragile X Syndrome. [PDF]
Xie L+7 more
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RNA-binding proteins in disease etiology: fragile X syndrome and spinal muscular atrophy. [PDF]
Dreyfuss G.
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A near normal distribution of IQ in Fragile X Syndrome. [PDF]
Schmitt LM+3 more
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Hippocampal-prefrontal functional neural networks in a rat model of fragile X syndrome are poorly organized with limited resiliency. [PDF]
Ouardouz M+5 more
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Adaptive functioning in children and young adults with monogenic neurodevelopmental disorders
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16264 Abstract Aim To examine the adaptive behaviour profiles of children with monogenic neurodevelopmental disorders (NDDs) to determine whether syndrome‐specific or transdiagnostic approaches provide a better understanding of the adaptive behavioural phenotypes of these NDDs ...
Emma K. Baker+8 more
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Compensatory Regulation of Excitation/Inhibition Balance in the Ventral Hippocampus: Insights from Fragile X Syndrome. [PDF]
Papatheodoropoulos C.
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