Results 141 to 150 of about 125,088 (254)

Ageing reveals the latent effects of early life stress on respiratory and metabolic function in female rats: Novel insights into the sex‐specific origins of sleep apnoea

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is ∼2 times more prevalent in men than women. However, this changes at menopause as the occurrence of SA increases and matches that of men. Menopause is a natural process, but it remains unclear why SA emerges only in a subpopulation of ageing women.
Danuzia Ambrozio‐Marques, Loralie Mei Guay, Alicia A. Koogler, Tim D. Ostrowski, Richard Kinkead   +4 more
wiley   +1 more source

Defining genetically meaningful language and personality traits in relatives of individuals with fragile X syndrome and relatives of individuals with autism

, 2012
Molly Losh, Jessica Klusek, Gary E. Martin, John Sideris, Morgan Parlier, Joseph Piven   +5 more
openalex   +2 more sources

Sleep in a mouse model of fragile X syndrome is resistant to metabolic manipulations. [PDF]

Hum Mol Genet
Lopez Valencia M, Velázquez Aponte RA, Baur JA, Jongens TA, Sehgal A.   +4 more
europepmc   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

Experimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė, Erinija Pranckevičienė, Alina Urnikytė, Laura Jurkūnaitė, Kristijona Gutauskaitė, Rūta Dadelienė, Justina Kilaitė, Ieva Eglė Jamontaitė, Asta Mastavičiūtė, Ildus I. Ahmetov, Vidmantas Alekna   +10 more
wiley   +1 more source

Molecular analysis of FMR1 alleles for fragile X syndrome diagnosis and patient stratification [PDF]

, 2020
Daman Kumari, Karen Usdin
openalex   +1 more source

Impaired thalamic burst firing in fragile X syndrome. [PDF]

Cell Rep
O'Shea RT, Priebe NJ, Brager DH.
europepmc   +1 more source

Fmr1 knockout disrupts multiple intrinsic properties via reduced HCN channel activity in mediodorsal thalamocortical neurons

Experimental Physiology, EarlyView.
Abstract The neurodevelopmental disorder fragile X syndrome (FXS) results from hypermethylation of the FMR1 gene, which prevents production of the FMRP protein. FMRP modulates the expression and function of a variety of proteins, including voltage‐gated ion channels, such as hyperpolarization‐activated and cyclic nucleotide‐gated (HCN) channels, which ...
Gregory J. Ordemann, Polina Lyuboslavsky, Alena Kizimenko, Audrey C. Brumback   +3 more
wiley   +1 more source

Age‐ and CGG repeat‐related slowing of manual movement in fragile X carriers: A prodrome of fragile X‐associated tremor ataxia syndrome?

, 2018
Ryan Shickman, Jessica Famula, Flora Tassone, Maureen A. Leehey, Emilio Ferrer, Susan M. Rivera, David Hessl   +6 more
openalex   +2 more sources

Elevated serotonin receptor 2A signaling restores learning and memory in a Fragile X syndrome model. [PDF]

Sci Rep
Du Y, Miller VK, Mellies AJ, Broadie K.
europepmc   +1 more source

Component analysis of a self‐monitoring intervention for increasing task engagement for individuals with developmental disabilities

Journal of Applied Behavior Analysis, Volume 59, Issue 2, Spring 2026.
Abstract Self‐monitoring (SM) has been used as part of intervention packages to enhance skills such as leisure and vocational engagement for individuals with intellectual and developmental disabilities (IDD). However, the effectiveness of SM alone remains unclear.
Erin Leif, Eileen Roscoe, Lauren Rae, Sam Sheets   +3 more
wiley   +1 more source