Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao +8 more
wiley +1 more source
Assessing Autism Co-Occurrence in Fragile X Syndrome: Proposing a Preliminary CARS-2 Cut-Off Score [PDF]
Tiffany Chavers +5 more
openalex +1 more source
A 30-Year Experience in Fragile X Syndrome Molecular Diagnosis from a Laboratory in Thailand. [PDF]
Hnoonual A +4 more
europepmc +1 more source
Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen +8 more
wiley +1 more source
Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J Background [PDF]
Bosong Wang +3 more
openalex +1 more source
Aberrant hippocampal gamma oscillations in a mouse model of fragile X syndrome: insights from in vitro slice models. [PDF]
Pollali E +7 more
europepmc +1 more source
ABSTRACT Objective We aim to increase knowledge on pregnancy and delivery risks in vascular Ehlers–Danlos Syndrome (vEDS). Our outcomes can contribute to establishing future guidelines for pregnancy and delivery management in women with vEDS. Design Retrospective multicentre cohort study.
Lisa M. van den Bersselaar +13 more
wiley +1 more source
Aberrant differentiation of glutamatergic cells in neocortex of mouse model for fragile X syndrome
Topi A. Tervonen +7 more
openalex +2 more sources
Correction: A sensitive and reproducible qRT-PCR assay detects physiological relevant trace levels of FMR1 mRNA in individuals with Fragile X syndrome. [PDF]
Straub D +6 more
europepmc +1 more source
Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli +3 more
wiley +1 more source

