Results 211 to 220 of about 7,289,232 (294)

ERK-dependent hyperexcitability of BLA neurons projecting to dCA3 underlies social dysfunction in a male mouse model of fragile X syndrome. [PDF]

EBioMedicine
Wang S, Wu X, Dong S, Zheng L, Pan L, Zhan L, Xiao H, Yang L, Wang X, Ma H, Xu H, Pan B, Wang L, Wang H.   +13 more
europepmc   +1 more source

Expanding the Utility of Exome Sequencing in Preventive and Population Genetics

American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2433-2442, November 2026.
ABSTRACT Carrier screening is a long‐standing genetic testing process offered to at‐risk couples, with or without a family history, who might have pregnancies affected by an autosomal recessive (AR) or X‐linked (XL) disorder. A total of 276 unrelated individuals, initially referred for rare disorder screening by clinicians, were enrolled in this study ...
Charilaos Kostoulas, Athanasia Sesse, Ioanna Bouba, Robert Najdecki, Spyridon Konitsiotis, Sofia Markoula, Ioannis Georgiou   +6 more
wiley   +1 more source

Fragile X Syndrome in Adulthood: A Study of Electronic Health Records. [PDF]

Am J Intellect Dev Disabil
Movaghar A, Smith DaWalt L, Brilliant M, Kho A, Magana S, Berry-Kravis EM, Mailick MR.   +6 more
europepmc   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

Advanced NanoBiomed Research, Volume 6, Issue 11, November 2026.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman, Shripad S. Hebbar, Rishikesh Balvalli, Manasa Nune   +3 more
wiley   +1 more source

Capturing Phenotypic Heterogeneity in Differentiated Sensory Processing Profiles: Non-Syndromic Autism and Fragile X Syndrome. [PDF]

Autism
Knott CE, Roberts JE, Will EA.
europepmc   +1 more source

Fecal Microbiota Transplantation: A Promising Therapeutic Strategy Targeting the Microbiota–Gut–Brain Axis in Anorexia Nervosa

Brain and Behavior, Volume 16, Issue 11, November 2026.
Gut dysbiosis in anorexia nervosa may impair microbiota–gut–brain signaling through metabolic, immune, and vagal pathways. Fecal microbiota transplantation is being investigated as a potential strategy to restore host–microbiome balance, support a healthier microbial composition, and improve gastrointestinal function, appetite, and mood.
Shawn L. Kwok, Yu‐Chen Xiao, Xian‐Bin Cai   +2 more
wiley   +1 more source

Gene Therapy for Fragile X Syndrome, Challenges, and Promises. [PDF]

J Gene Med
Velinov M.
europepmc   +1 more source

Posttranslational Modification Cross‐Talk in Vascular Cells: Molecular Mechanisms and Therapeutic Implications for Atherosclerosis

Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Atherosclerosis is driven by coordinated changes in endothelial cells (ECs), macrophages, and vascular smooth muscle cells (VSMCs). Post‐translational modifications (PTMs), phosphorylation, acetylation, ubiquitination, SUMOylation, O‐GlcNAcylation, palmitoylation, ISGylation, and ADP‐ribosylation, integrate metabolic, inflammatory, and ...
Weiwei Jiang, Haiping Du
wiley   +1 more source

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome-linked mutations. [PDF]

FEBS J
Catalano F, Bigi A, Troilo F, Gabriele F, Pistoia G, Asteriti IA, Angelucci F, Giardina G, Chiti F, Travaglini-Allocatelli C, Di Matteo A.   +10 more
europepmc   +1 more source

Management of advanced mycosis fungoides and Sézary Syndrome: International Recommendations for systemic treatments and allogeneic hematopoietic cell transplantation from the European Hematology Association, the EORTC Cutaneous Lymphoma Tumours Group, the International Society for Cutaneous Lymphoma, and the Lymphoma Working Party of the EBMT

HemaSphere, Volume 10, Issue 11, November 2026.
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida, Pietro Quaglino, Julia Scarisbrick, Anna Sureda, Emmilia Hodak, Evangelia Papadavid, Silvia Alberti‐Violetti, Martine Bagot, Lorenzo Cerroni, Amrita Goyal‐O'Leary, Rudolf Stadler, Rein Willemze, Jasmine Zain, Marco Ardigò, Emilio Berti, Adèle de Masson, Rafael F. Duarte, Francine Foss, Eva González‐Barca, Joan Guitart, Pablo Ortiz‐Romero, Alessandro Pileri, Pierluigi Porcu, Henry M. Prince, Sima Rozati, Serena Rupoli, Maarten H. Vermeer, Sean Whittaker, Nicola Pimpinelli, Pier Luigi Zinzani   +29 more
wiley   +1 more source