Results 1 to 10 of about 165,426 (165)
BMJ, 1963 Introduction When mental retardation is suspected early during a child's life, it is the pediatrician who is usually confronted with the problems of diagnosis and the difficulties of parental counseling. Pediatricians are also assuming increasing responsibilities in community programs for retarded children.
Z, STEIN, M, SUSSER
+8 more sources
Cell Communication and Signaling, 2023 Background Microglial cells play an important role in the immune system in the brain. Activated microglial cells are not only injurious but also neuroprotective.
Yoshinori Aoki +8 more
doaj +1 more source
Duplication within two regions distal to MECP2: clinical similarity with MECP2 duplication syndrome
BMC Medical Genomics, 2023 Background X-linked methyl-CpG-binding protein 2 (MECP2) duplication syndrome is prevalent in approximately 1% of X-linked intellectual disabilities. Accumulating evidence has suggested that MECP2 is the causative gene of MECP2 duplication syndrome.
Keiko Akahoshi +3 more
doaj +1 more source
Group Intensive Cognitive Activation in Patients with Major or Mild Neurocognitive Disorder
Frontiers in Behavioral Neuroscience, 2016 Background: No standard protocols are available for cognitive rehabilitation in conditions like Major or Mild Neurocognitive disorder (M-NCD or m-NCD, respectively); however, preliminary data seem to indicate that such interventions might have cost ...
Simonetta ePanerai +9 more
doaj +1 more source
LDOC1 expression in fibroblasts of patients with Down syndrome
Open Life Sciences, 2015 Down syndrome (DS) is characterised by intellectual disability and is caused by trisomy 21. Apoptosis is a programmed cell death process and is involved in neurodegenerative diseases such as Alzheimer.
Salemi Michele +11 more
doaj +1 more source
Journal of Lipid Research, 1974 Rat brain 1,2-diacyl-sn-glycerols (diglycerides) and 1,2-diacyl-sn-glycerols obtained from 1,2-diacyl-sn-glycero-3-phosphorylcholine after treatment with phospholipase C differ markedly in carbon number distribution.
J.F. O'Brien, R.L. Geison
doaj +1 more source
Behavioural Neurology, 2010 Wakefulness, rapid eye movement (REM) and non-REM sleep are not always mutually exclusive conditions, as commonly assumed. In some cases, the declaration of any state may be incomplete and states can fluctuate rapidly, resulting in peculiar behavioural ...
Alberto Raggi +3 more
doaj +1 more source
Esterification of fatty acids at room temperature by chloroform-methanolic HCl–cupric acetate
Journal of Lipid Research, 1973 A new procedure for the preparation of methyl esters from free fatty acids under mild conditions was investigated. Free fatty acids are dissolved in a mixture of chloroform–methanolic HCl–cupric acetate and kept at room temperature for 30 min for ...
Motonori Hoshi +2 more
doaj +1 more source
The genetics of mental retardation [PDF]
British Medical Bulletin, 1996 We review the advances that have been achieved using molecular genetic techniques to characterise the genetic basis of mental retardation in recognised syndromes and in discovering new genetic conditions that give rise to mental retardation. However, even with the cloning of a number of mutant genes, the pathogenesis of the condition is not understood.
Flint, J, Wilkie, A
openaire +3 more sources
Stability of Auditory Discrimination and Novelty Processing in Physiological Aging
Behavioural Neurology, 2013 Complex higher-order cognitive functions and their possible changes with aging are mandatory objectives of cognitive neuroscience. Event-related potentials (ERPs) allow investigators to probe the earliest stages of information processing.
Alberto Raggi +3 more
doaj +1 more source