Results 251 to 260 of about 225,713 (333)

Dysregulation and restoration of translational homeostasis in fragile X syndrome

Nature Reviews Neuroscience, 2015
J. Richter, G. Bassell, E. Klann
semanticscholar   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Exploring the Relationship Between Fragile X Syndrome and Autism: A Bibliometric Analysis of Global Research Trends. [PDF]

Cureus
Kaplan A, Malik S, Persaud NA, Ganti L.
europepmc   +1 more source

Public Health Literature Review of Fragile X Syndrome

Pediatrics, 2017
M. Raspa, A. Wheeler, C. Riley
semanticscholar   +1 more source

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu, Ju‐Chan Park, Heesoo Uhm, Yong‐Woo Kim, Hyeon Woo Im, Sangsu Bae   +5 more
wiley   +1 more source

Scheduled feeding improves behavioral outcomes and reduces inflammation in a mouse model of fragile X syndrome. [PDF]

Elife
Wang HB, Smale NE, Brown SH, Villanueva SAMB, Zhou D, Mulji A, Bhandal DS, Nguyen-Ngo K, Harvey JR, Ghiani CA, Colwell CS.   +10 more
europepmc   +1 more source

Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics

Aggregate, Volume 7, Issue 3, March 2026.
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang, Ruixuan Zheng, Jing Lin, Jiawu Weng, Lexiang Zhang, Fangfu Ye   +5 more
wiley   +1 more source

Delayed structural maturation of inner hair cell ribbon synapses in a mouse model of fragile X syndrome. [PDF]

Front Mol Neurosci
Chojnacka M, Skupien-Jaroszek A, Dziembowska M.   +2 more
europepmc   +1 more source

Late Pregnancy Antiseizure Medication Exposure and Offspring Neurodevelopmental Risk: A Multi‐Child Cohort Study

Annals of Neurology, Volume 99, Issue 3, Page 761-776, March 2026.
Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy, Vanina Tchuente, Sherif Eltonsy, Steven Hawken, Padma Kaul, Mark Walker, Michael Pugliese, Roxana Dragan, Anamaria Savu, Lisiane Leal, Lucie Morin, Isabelle Malhamé, Raluca Pana, Anick Bérard   +13 more
wiley   +1 more source

Activity of Human-Specific Interlaminar Astrocytes in a Chimeric Mouse Model of Fragile X Syndrome. [PDF]

Int J Mol Sci
Anding A, Ren B, Padmashri R, Burkovetskaya M, Dunaevsky A.   +4 more
europepmc   +1 more source