Results 61 to 70 of about 20,103 (170)

N‐Acetylglucosamine Selectively Attenuates Neuroinflammation in a Mouse Model of Mitochondrial Dysfunction

open access: yesActa Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Mitochondrial dysfunction plays a central role in multiple neurodegenerative diseases, yet the temporal sequence of cellular events underlying neurodegeneration remains poorly defined. This study aimed to characterize the progression of neurodegeneration in a mouse model of fatal mitochondrial encephalopathy and to evaluate the therapeutic
Laura Jiménez‐Sánchez   +12 more
wiley   +1 more source

Trayectorias de fragilidad física en adultos mayores del estudio IMIAS

open access: yes, 2023
Ilustraciones, gráficas, mapasLa fragilidad es un síndrome caracterizado por su naturaleza dinámica, prevenible y tratable. Tiene resultados adversos en la salud del adulto mayor como hospitalización, caídas, discapacidad y muerte.
BENJUMEA SALGADO, ANGELA MARIA
core  

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 3, Page 658-668, March 2026.
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Adriana Abizanda Saro   +86 more
wiley   +1 more source

La precariedad y su constelación léxico-semántica

open access: yesPensamiento. Revista de Investigación e Información Filosófica, 2020
Este artículo está dedicado a enmarcar la categoría de precariedad en un contexto amplio constituido por un conjunto de autores como J. Butler, G. Vattimo, J. Habermas o M. Nussbaum.
Anisa Azaovagh de la Rosa
doaj   +1 more source

Differential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1498-1512, 1 March 2026.
Abstract figure T‐type VGCCs contribute to the contraction of the rabbit aorta and modulate both contraction and vasodilation in the rabbit renal artery. α1, alpha 1 adrenergic receptor; ATR, angiotensin II receptor; Ang II, angiotensin II; CaM, calmodulin; Cav3, T‐type voltage‐gated Ca2⁺ channels; cGMP, cyclic guanidine monophosphate; EC, endothelial ...
Andrea Suarez   +6 more
wiley   +1 more source

Formar profesionales competentes [PDF]

open access: yes, 2007
El compromiso de toda universidad no se limita solamente al otorgamiento y adquisición de conocimientos técnicos, científicos, sino que debe preparar a los alumnos para el desafío de su inserción laboral dentro de un mundo diverso y cambiante.
Fittipaldi, María José
core  

Síndrome de fragilidad del adulto mayor

open access: yes, 2023
Actualmente la frecuencia de fragilidad en adultos mayores es del 7,7 % y de la pre fragilidad es el 64,6% y nuestro punto de corte de la velocidad de la marcha es el 0,7.
Montesinos Trujillano, Sol
core  

Fragilidad: un constructo complejo que requiere claridad teórica [PDF]

open access: yes
La fragilidad es uno de los términos más ampliamente discutidos en la literatura científica relacionada con el envejecimiento. Introducido inicialmente a principios de los años 2000, este concepto ha tenido un alto impacto en la comunidad científica ...
Fierro-Marrero, José
core   +2 more sources

Detecting early memory changes in preclinical Alzheimer's disease using TabCAT favorites test: Data from the European Prevention of Alzheimer's Disease (EPAD) cohort

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sensitive memory paradigms may allow the detection of subtle memory changes associated with early Alzheimer's pathology in individuals without established clinical symptomatology. METHODS We explored the cross‐sectional association between performance on Tablet‐based Cognitive Assessment Tool (TabCAT) Favorites, a brief ...
Anna Brugulat‐Serrat   +9 more
wiley   +1 more source

Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep disruption, particularly loss of slow‐wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus coeruleus (LC) integrity relates to SWS across the AD continuum and whether sex and perivascular spaces (PVSs) modify these associations.
Neus Falgàs   +20 more
wiley   +1 more source

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