Results 181 to 190 of about 1,654,002 (384)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Impacts of the anthropic activities on the fragmentation of the habitats of the fauna of the Bénoué National Park

, 2022
Tchobsala, Godwe Gara Jean Marie, Aoudou Sylvin, Ibrahima Adamou, Mbamba Mbamba Jean Paul Kevin   +4 more
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

MP24-10 WAVELENGTH AND PULSE SHAPE EFFECTS ON STONE FRAGMENTATION OF LASER LITHOTRIPTERS [PDF]

, 2018
Andreas J. Gross, Benedikt Becker, Mark Taratkin, Dmitry Enikeev, Л. М. Рапопорт, Christopher Netsch   +5 more
openalex   +1 more source

Bryologische Fragmente [PDF]

Oesterreichische Botanische Zeitschrift, 1904
openaire   +2 more sources

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Lost in fragmentation — care coordination when somatic symptoms persist: a qualitative study of patients’ experiences [PDF]

, 2022
Hieke Barends, Femke Botman, Ella Walstock, Nikki Claassen-van Dessel, Johannes C. van der Wouden, Tim olde Hartman, Joost Dekker, Henriëtte E. van der Horst   +7 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Is habitat fragmentation bad for biodiversity?

Biological Conservation, 2019
L. Fahrig, V. Arroyo‐Rodríguez, J. Bennett, Véronique Boucher-Lalonde, E. Cazetta, D. Currie, F. Eigenbrod, A. Ford, S. Harrison, Jochen A. G. Jaeger, N. Koper, Amanda E. Martin, Jean-Louis Martin, J. Metzger, Peter Morrison, J. Rhodes, D. Saunders, D. Simberloff, Adam C. Smith, L. Tischendorf, M. Vellend, James I. Watling   +21 more
semanticscholar   +1 more source

Sperm DNA fragmentation testing in clinical management of reproductive medicine [PDF]

, 2023
Ava Adler, Bradley J. Roth, Scott D. Lundy, Teppei Takeshima, Yasushi Yumura, Shinnosuke Kuroda   +5 more
openalex   +1 more source