Results 41 to 50 of about 3,071,234 (393)

Controlling Fragment Competition on Pathways to Addressable Self-Assembly [PDF]

open access: yesThe Journal of Physical Chemistry B, 2018
Addressable self-assembly is the formation of a target structure from a set of unique molecular or colloidal building-blocks, each of which occupies a defined location in the target. The requirement that each type of building-block appears exactly once in each copy of the target introduces severe restrictions on the combinations of particles and on the
Jim Madge, David Bourne, Mark A. Miller
openaire   +4 more sources

Differentiating signals to make biological sense – a guide through databases for MS-based non-targeted metabolomics [PDF]

open access: yes, 2017
Metabolite identification is one of the most challenging steps in metabolomics studies and reflects one of the greatest bottlenecks in the entire workflow.
Armitage, Emily Grace   +4 more
core   +1 more source

Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]

open access: yes, 2010
Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
core   +1 more source

Distinct functions for the Drosophila piRNA pathway in genome maintenance and telomere protection. [PDF]

open access: yesPLoS Genetics, 2010
Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has
Jaspreet S Khurana   +3 more
doaj   +1 more source

Alachlor oxidation by the filamentous fungus Paecilomyces marquandii [PDF]

open access: yes, 2013
Alachlor, a popular chloroacetanilide herbicide, can be a potential health risk factor. Soil microorganisms are primarily responsible for conversion and migration of alachlor in natural environment, but knowledge concerning alachlor biodegradation is not
Długoński, Jerzy   +3 more
core   +1 more source

Melatonin prevents Drp1‐mediated mitochondrial fission in diabetic hearts through SIRT1‐PGC1α pathway

open access: yesJournal of Pineal Research, 2018
Myocardial contractile dysfunction is associated with an increase in mitochondrial fission in patients with diabetes. However, whether mitochondrial fission directly promotes diabetes‐induced cardiac dysfunction is still unknown.
Mingge Ding   +10 more
semanticscholar   +1 more source

Study of Chemical Components and Fragmentation Pathways of Semen Lepidii by UPLC-Orbitrap-MS/MS

open access: yesZhipu Xuebao
Semen Lepidii is the dried and mature seeds of the cruciferous plant of Descurainia Sophia or Lepidium Apetalum, being a widely-used traditional Chinese medicine for various pharmacological effects, such as antibacterial, antitumor, diuretic and ...
Xiao TIAN   +5 more
doaj   +1 more source

Excessive mitochondrial fragmentation triggered by erlotinib promotes pancreatic cancer PANC-1 cell apoptosis via activating the mROS-HtrA2/Omi pathways

open access: yesCancer Cell International, 2018
Background Mitochondrial fragmentation drastically regulates the viability of pancreatic cancer through a poorly understood mechanism. The present study used erlotinib to activate mitochondrial fragmentation and then investigated the downstream events ...
Jun Wan   +7 more
doaj   +1 more source

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. [PDF]

open access: yesPLoS ONE, 2010
Loss-of-function mutations in the PINK1 or parkin genes result in recessive heritable forms of parkinsonism. Genetic studies of Drosophila orthologs of PINK1 and parkin indicate that PINK1, a mitochondrially targeted serine/threonine kinase, acts ...
Angela C Poole   +4 more
doaj   +1 more source

Effector Caspase Dcp-1 and IAP Protein Bruce Regulate Starvation-Induced Autophagy during Drosophila Melanogaster Oogenesis [PDF]

open access: yes, 2008
A complex relationship exists between autophagy and apoptosis, but the regulatory mechanisms underlying their interactions are largely unknown. We conducted a systematic study of Drosophila melanogaster cell death–related genes to determine their ...
Barbosa, Sharon González   +4 more
core   +4 more sources

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