Results 51 to 60 of about 3,071,234 (393)

Pathways to Fragmentation [PDF]

Proceedings of the 10th ACM Conference on Web Science, 2018
This study analyzes how web audiences flow across online digital features. We construct a directed network of user flows based on sequential user clickstreams for all popular websites (n=1761), using traffic data obtained from a panel of a million web users in the United States.
Taneja, Harsh, Wu, Angela Xiao
openaire   +2 more sources

Mass Fragmentation Characteristics of t-Boc Substituted Drug Precursors

Zhipu Xuebao
To circumvent the supervision of law, illicit manufacturers turn to produce drug related precursors. Among them, tert-butoxycarbonyl (t-Boc) substituted drug precursors are the most common type recently.
Cui-mei LIU, Xue-yan LIU, Zhen-dong HUA, Hao TANG, Yu DU, Wei JIA   +5 more
doaj   +1 more source

Abnormal ECG Findings in Athletes: Clinical Evaluation and Considerations. [PDF]

, 2019
PURPOSE OF REVIEW: Pre-participation cardiovascular evaluation with electrocardiography is normal practice for most sporting bodies. Awareness about sudden cardiac death in athletes and recognizing how screening can help identify vulnerable athletes have
A Biffi, A Biffi, A D’Silva, A D’Silva, A Magalski, A Malhotra, A Malhotra, A Malhotra, A Merghani, A Morshedi-Meibodi, A Pelliccia, A Pelliccia, A Zaidi, A Zaidi, A Zorzi, A Zorzi, A Zorzi, AD Desai, AL Aro, AL Rao, AO Usoro, BJ Maron, BJ Maron, C Antzelevitch, C Calore, C Daubert, C Miles, D Corrado, D Corrado, D Corrado, D Corrado, F D’Ascenzi, F Migliore, F Schnell, FI Marcus, G Finocchiaro, G Malfatto, G Mcclean, GJ Klein, GJ Klein, H Dhutia, H Morita, HUH Virk, J Basu, J Ehtisham, J Marek, J Novak, J Pei, J Steinfurt, JA Drezner, JA Drezner, KG Harmon, KM Park, L Calò, L Verdile, M Brosnan, M Papadakis, M Papadakis, M Sadron Blaye-Felice, MAE Haukilahti, Mark Abela, MG Wilson, MI Cohen, MJ Ackerman, MJ Brosnan, N Chandra, N Panhuyzen-goedkoop, N Sheikh, P Banankhah, PG Postema, PT Matusik, RE Bent, RE Eckart, S Gati, S Kapa, S Masrur, S Peters, S Sharma, S Viskin, Sanjay Sharma, SEE Page, T Senturk, X Li, YH Lee   +83 more
core   +1 more source

Hyperglycaemia Stress-Induced Renal Injury is Caused by Extensive Mitochondrial Fragmentation, Attenuated MKP1 Signalling, and Activated JNK-CaMKII-Fis1 Biological Axis

Cellular Physiology and Biochemistry, 2018
Background/Aims: Hyperglycaemia stress-induced renal injury is closely associated with mitochondrial dysfunction through poorly understood mechanisms. The aim of our study is to explore the upstream trigger and the downstream effector driving diabetic ...
Yunfang Zhang, Junxia Feng, Qi Wang, Shili Zhao, Shen Yang, Lu Tian, Ping Meng, Jingchun Li, Hongyan Li   +8 more
doaj   +1 more source

Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics. [PDF]

, 2018
The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured elucidation approaches and software that are designed to help during the annotation of unknown compounds.
Blaženović, Ivana, Fiehn, Oliver, Ji, Jian, Kind, Tobias   +3 more
core   +3 more sources

Identification and Mass Spectrometric Fragmentation Pathways of Chemical Components in the Traditional Chinese Medicine Formula of Jiuwei Decoction

Zhipu Xuebao
Traditional Chinese medicine (TCM), both a longstanding medical practice in Asia and an increasingly utilized supplement or alternative medicine in Western countries, has become a focal point within the life sciences in recent years.
Jia-yu ZHAO, Yue-guang LYU, Tong XIN, Qian-qian GUO, Wen-ying ZHANG, Jin-hong LI, Hong-yu XUE, Qiang MA   +7 more
doaj   +1 more source

Differential involvement of caspase-6 in amyloid-β-induced fragmentation of lamin A and B

Biochemistry and Biophysics Reports, 2020
Amyloid-β (Aβ), a peptide implicated in Alzheimer's disease, was shown to cause specific fragmentation of lamin proteins, which was mediated by an unidentified protease named nuclear scaffold protease (NSP) independently of caspase-6.
Md Imamul Islam, Md Selim Hossain, Il-Seon Park   +2 more
doaj   +1 more source

Unravelling an oxygen-mediated reductive quenching pathway for photopolymerisation under long wavelengths

Nature Communications, 2021
Photomediated-reversible-deactivation radical polymerisation has a limited scope of available photocatalysts due to multiple stringent requirements of properties.
Chenyu Wu, Kenward Jung, Yongtao Ma, Wenjian Liu, Cyrille Boyer   +4 more
doaj   +1 more source

The invertebrate Caenorhabditis elegans biosynthesizes ascorbate. [PDF]

, 2015
l-Ascorbate, commonly known as vitamin C, serves as an antioxidant and cofactor essential for many biological processes. Distinct ascorbate biosynthetic pathways have been established for animals and plants, but little is known about the presence or ...
Adler, Lital N, Budenholzer, Lauren M, Clarke, Steven G, Patananan, Alexander N, Pedraza, Maria E, Torres, Eric R   +5 more
core   +2 more sources

CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway

OncoTarget, 2017
Cancer cells exhibit an abnormal amino acid metabolism and a dependence on specific amino acids, which might provide potential targets for treating cancer patients. In this study, we demonstrated that human triple negative breast cancer (TNBC) cells were
Meng-Shian Chen, Sheng-Fan Wang, Chih‐Yi Hsu, P. Yin, Tien‐Shun Yeh, Hsin-Chen Lee, L. Tseng   +6 more
semanticscholar   +1 more source