Results 101 to 110 of about 874,378 (337)

Effect of Preventive Home Visits by a Nurse on the Outcomes of Frail Elderly People in the Community: a randomized controlled trial [PDF]

open access: yes, 2000
Background: Timely recognition and prevention of health problems among elderly people have been shown to improve their health. In this randomized controlled trial the authors examined the impact of preventive home visits by a nurse compared with usual ...
Dalby, Dawn M.   +5 more
core   +2 more sources

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

open access: yesAdvanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen   +31 more
wiley   +1 more source

Family Caregiving to the Older Population: Background, Federal Programs, and Issues for Congress [PDF]

open access: yes, 2007
[Excerpt] Family caregiving to older individuals in need of long-term care encompasses a wide range of activities, services, and supports. Caregiving can include assistance with personal care needs, such as bathing, dressing, and eating, as well as other
Colello, Kirsten J.
core   +3 more sources

Determinants of frailty development and progression using a multidimensional frailty index: Evidence from the English Longitudinal Study of Ageing [PDF]

open access: yes, 2019
This work was supported by grant number 689592 "my-AHA" from the Horizon 2020 research funding framework of the European Commission (https://ec.europa.eu/programmes/horizon2020/en).Open Access ...
Bandelow, Stephan   +2 more
core   +3 more sources

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

Correlation of FRAIL scale and fragile index with adverse outcomes in elderly patients on maintenance hemodialysis

open access: yesLinchuang shenzangbing zazhi
Objective To explore the FRAIL scale and fragile index (FI) and adverse outcomes of elderly maintenance hemodialysis (MHD) patients. Methods From June 2020 to December 2022, 116 elderly patients on MHD were selected and assigned into two groups of ...
Fang Jin, Li-qun Gao, Su-xia Wang
doaj   +1 more source

Rituximab plus bendamustine as front-line treatment in frail elderly (>70 years) patients with diffuse large B-cell non-Hodgkin lymphoma: a phase II multicenter study of the Fondazione Italiana Linfomi

open access: yesHaematologica, 2018
We conducted a phase II study to assess activity and safety profile of bendamustine and rituximab in elderly patients with untreated diffuse large B-cell lymphoma (DLBCL) who were prospectively defined as frail using a simplified version of the ...
S. Storti   +23 more
semanticscholar   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

open access: yesAdvanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl   +12 more
wiley   +1 more source

Integrated Telehealth and Telecare for Monitoring Frail Elderly with Chronic Disease

open access: yesTelemedicine journal and e-health, 2018
Objective: To investigate the potential of an integrated care system that acquires vital clinical signs and habits data to support independent living for elderly people with chronic disease.
Hulya Gokalp   +5 more
semanticscholar   +1 more source

From Grave to Cradle: Kombucha Waste for Sustainable Electronics

open access: yesAdvanced Science, EarlyView.
This study introduces a sustainable method to purify kombucha bacterial cellulose (KBC) with sodium bicarbonate and hydrogen peroxide, avoiding harsh chemicals. KBC films are patterned with gold and function as pressure sensors for flatfoot gait detection. At the end‐of‐life, the KBC‐based device biodegrades in soil, leaving environmentally benign gold
Xin Ying Chan   +6 more
wiley   +1 more source

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