Results 31 to 40 of about 611,461 (294)

Multifaceted antibiotic stewardship intervention using a participatory-action-research approach to improve antibiotic prescribing for urinary tract infections in frail elderly (ImpresU): study protocol for a European qualitative study followed by a pragmatic cluster randomised controlled trial

, 2021
Introduction Almost 60% of antibiotics in frail elderly are prescribed for alleged urinary tract infections (UTIs). A substantial part of this comprises prescriptions in case of non-specific symptoms or asymptomatic bacteriuria, for which the latest ...

core   +1 more source

The relationship between frailty in older adults and anxiety and depression in china: propensity score matching and network analysis

Frontiers in Psychiatry
ObjectiveAnxiety and depression are common mental disorders in the elderly. Concurrent frailty may lead to worse clinical outcomes. This study examined the network structures of anxiety and depression in frail and non-frail older adults.MethodsThe Center
Yinglin Li, Ling Zhao, Doudou Lin, Xinmei Wang, Chunlong Zhang, Jiali Zhou, Zhongxiang Cai   +6 more
doaj   +1 more source

A conceptual analysis of subjective health status in frail elderly Korean men [PDF]

Journal of Men's Health
This study seeks to define and examine the concept of subjective health status among the frail elderly Korean men. Using the concept analysis framework by Walker and Avant, 10 articles related to the subjective health status of frail elderly adults ...
Eun Jeong Nam, Sun Jung Park
doaj   +1 more source

Values and long-term care decision-making for frail elderly people [PDF]

, 2006
This project explored the values considered by elderly people, their younger relatives, and health professionals in decisions about residential long - term care, aiming to contribute to the literature on prospectively held values.
Denson, Linley Alice
core  

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study

Annals of Intensive Care
Objective To understand the impact of both frailty and chronologic age on outcomes of weaning from invasive mechanical ventilation (MV). Methods The study population consisted of patients enrolled in the ‘WorldwidE.
Caoimhe M. Laffey, Rionach Sheerin, Omid Khazaei, Bairbre A. McNicholas, Tài Pham, Leo Heunks, Giacomo Bellani, Laurent Brochard, Dana Tomescu, Andrew J. Simpkin, John G. Laffey, on behalf of the WEAN SAFE Investigators   +11 more
doaj   +1 more source

The predictive validity of three self-report screening instruments for identifying frail older people in the community

BMC Public Health, 2012
Background If brief and easy to use self report screening tools are available to identify frail elderly, this may avoid costs and unnecessary assessment of healthy people.
Daniels Ramon, van Rossum Erik, Beurskens Anna, van den Heuvel Wim, de Witte Luc   +4 more
doaj   +1 more source

Pitfalls in imaging the frail elderly [PDF]

The British Journal of Radiology, 2015
The number of older people in the UK is rising and will continue to increase. Furthermore, there is evidence that (i) the number of investigations on the oldest patients is disproportionately increasing, (ii) inappropriate and/or futile radiological investigations are commonplace and (iii) the requests are coming from the most junior doctors.
R, Fawcett, P, McCoubrie
openaire   +2 more sources

Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study. [PDF]

, 2022
OBJECTIVE: To develop and externally validate the STRAtifying Treatments In the multi-morbid Frail elderlY (STRATIFY)-Falls clinical prediction model to identify the risk of hospital admission or death from a fall in patients with an indication for ...
Griffin, Simon, Stevens, Richard, Snell, Kym I E, Archer, Lucinda, Hobbs, FD Richard, McManus, Richard J, Snell, Kym IE, Constantinos Koshiaris, Richard D Riley, Amitava Banerjee, Ogden, Margaret, F D Richard Hobbs, Usher-Smith, Juliet A, STRAtifying Treatments In the multi-morbid Frail elderlY (STRATI, James P Sheppard, Banerjee, Amitava, Richard Stevens, Snell, Kym I E; id_orcid, Koshiaris, Constantinos, Riley, Richard D; id_orcid, Kym I E Snell, Juliet A Usher-Smith, Andrew Clegg, Payne, Rupert A, Gladman, John, Clegg, Andrew, Lay-Flurrie, Sarah, Hobbs, F D Richard, Sheppard, James P, Lucinda Archer, Rupert A Payne, Riley, Richard D, Archer, Lucinda; id_orcid, Richard J McManus, Sarah Lay-Flurrie   +34 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source