Results 131 to 140 of about 180,045 (314)

[Frailty in the elderly]. [PDF]

Nederlands tijdschrift voor geneeskunde, 2009
Contains fulltext : 79796.pdf (Publisher’s version ) (Open Access)
Iersel, M.B. van, Jansen, D.R., Olde Rikkert, M.G.M.   +2 more
openaire   +1 more source

Novel biomarkers of frailty in middle-aged and older females

The burden of frailty and its associated health complications, including cardiovascular disease, is becoming a critical health concern. Frailty is a multifactorial physiological decline that increases vulnerability to health stressors.
Boreskie, Kevin
core  

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source

Unobserved heterogeneity in a model with cure fraction applied to breast cancer [PDF]

We suggest a cure-mixture model to analyze bivariate time-to-event data, as motivated by the paper of Chatterjee and Shih (2001, Biometrics 57, 779 - 786), but with a simpler estimation procedure and the correlated gamma-frailty model instead of the ...
Anatoli I. Yashin, Andreas Wienke, Paul Lichtenstein   +2 more
core  

Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury

Advanced Science, EarlyView.
A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu, Xiaoyang Wu, Xiaoyin Liu, Yuyan Wang, Shichao Jiang, Kai Wu, Gaowei Li, Jie Ding, Chengheng Wu, Dan Wei, Jing Sun, Hongsong Fan, Liangxue Zhou   +12 more
wiley   +1 more source

Clinical Presentation and Therapeutic Approach of Hepatic Sarcoidosis

Livers
Sarcoidosis is a multisystemic inflammatory disease defined by non-caseating granuloma formation in involved organs. The liver is the third most implicated organ after the lungs and lymph nodes.
Vittoria Benintende, Luca Bettazzoni, Nicola Reggidori, Chiara Ambrosi, Monica Patrignani, Luca Ielasi   +5 more
doaj   +1 more source

Frailty and nutrition

British Journal of Community Nursing
As the ageing population grows and forms a significant category of over 65s in many societies, along with it comes the risk of developing physical and psychological degenerative changes. This presents many challenges for health and social care services in not only identifying those at risk but also managing that risk to try to preserve health and ...
Wilson, Neil, Mullaney, William
openaire   +3 more sources

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

THE IMPACT OF AGE AND FRAILTY ON CARDIAC FUNCTION IN HEALTH AND DISEASE CONDITIONS IN NATURALLY AGEING MICE

, 2018
Frail people with cardiovascular disease experience worse outcomes and higher mortality than non-frail patients, but the links between frailty and myocardial function are unclear. Frailty was quantified as deficit accumulation in adult (≈8 mos) and aged (
Feridooni, Hirad
core  

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source