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Parametric Frailty and Shared Frailty Survival Models [PDF]
The Stata Journal: Promoting communications on statistics and Stata, 2002 Frailty models are the survival data analog to regression models, which account for heterogeneity and random effects. A frailty is a latent multiplicative effect on the hazard function and is assumed to have unit mean and variance θ, which is estimated along with the other model parameters. A frailty model is an heterogeneity model where the frailties
Roberto G. Gutierrez
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Orthopaedic surgeons’ perceptions of frailty and frailty screening [PDF]
BMC Geriatrics, 2020 Background Over the past decade, there has been significant growth in the awareness and understanding of fragility among orthopaedic surgeons in the context of osteoporotic fractures and with it, improvements in the recognition and management of ...
Mandy M. Archibald +3 more
doaj +5 more sources
Revista Clínica Española (English Edition), 2023 Objective: determine the extent to which each criterion of the frailty phenotype (either alone or grouped) contributes to the emergence of the syndrome in older people. Methods: observational and analytical study was conducted with 219 male and female older people in outpatient care.
Adrielle Cavalcanti de Pontes Araújo +3 more
+6 more sources
Zeitschrift für Gerontologie und Geriatrie, 2016 Frailty or infirmity is seen as a central element in the construction of the social imaginary of the fourth age. While the term is widely employed as a bio-medical condition that is capable of being defined and measured, this chapter argues that frailty serves as a marker – a signifier – of an almost intangible loss of capabilities, autonomy and status.
Paul Higgs, Chris Gilleard
+6 more sources
Postgraduate Medical Journal, 2007 Abstract The term “frailty” is used loosely to describe a range of conditions in older people, including general debility and cognitive impairment. There is no clear consensus on the definition of frailty; however, it is proposed that frailty comprises a collection of biomedical factors which influences an individual's physiological ...
Frank, Lally, Peter, Crome
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Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study. [PDF]
, 2020 Frailty results from the chronic effects of malnutrition and muscle wasting in patients with cirrhosis. It is well-established that frailty is strongly associated with mortality in this population.
Covinsky, Kenneth E +4 more
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Identifying characteristics of frailty in female mice using a phenotype assessment tool [PDF]
, 2019 Preclinical studies are important in identifying the underlying mechanisms contributing to frailty. Frailty studies have mainly focused on male rodents with little directed at female rodents.
Baumann, Cory W. +2 more
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Role of sarcopenia in the frailty transitions in older adults: a population‐based cohort study
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background Frailty and sarcopenia are age‐associated syndromes that have been associated with the risk of several adverse events, mainly functional decline and death, that usually coexist.
Alejandro Álvarez‐Bustos +6 more
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Journal of Aging Studies, 2022 Taking as a point of departure the role that the category of frailty increasingly plays in the classification, sorting and management of ageing populations in contemporary societies, this paper focuses on the crafting and validation of mouse models of frailty.
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Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist [PDF]
, 2016 AIM: To investigate the impact of physical frailty on risk of hospitalisation in cirrhotic patients on the liver transplant waitlist. METHODS: Cirrhotics listed for liver transplantation at a single centre underwent frailty assessments using the Fried ...
Dodge, Jennifer L +3 more
core +1 more source