Results 231 to 240 of about 264,721 (290)

Impact of frailty on outcomes in atrial fibrillation and HFpEF: data from the TOPCAT trial. [PDF]

BMC Cardiovasc Disord
Zhou L, Li CY, Zhang JR, Huang LH, Guo LZ, Li SN, Long DY, Dong JZ, Ma CS.   +8 more
europepmc   +1 more source

Impact of disease burden on VO₂max, physical performance and frailty in ankylosing spondylitis: a comparative cross-sectional study. [PDF]

BMJ Open
Tariq A, Ammar M, Saad A, Zadeh SAM.
europepmc   +1 more source

Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification

American Journal of Hematology, EarlyView.
ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
Sara El Aouhel, Vanessa Bellegarde, Stennio Da Silva Faria, Tristan St‐Laurent, Estelle Lecluze, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Frédéric Galactéros, Pablo Bartolucci, Marc‐André Legault, Guillaume Lettre, Thomas Pincez   +10 more
wiley   +1 more source

Sex-specific associations between frailty and long-term outcomes in patients with acute myocardial infarction: a national population-based study. [PDF]

Lancet Reg Health Eur
Mohiaddin H, Mosanya CH, Lawson C, Khunti K, Wood A, Squire IB, McCann GP, Damluji AA, Buccheri S, Alkhouli MA, Mamas MA, Rashid M.   +11 more
europepmc   +1 more source

Real‐World Effectiveness and Safety of Ravulizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria: Evidence From the International PNH Registry

American Journal of Hematology, EarlyView.
ABSTRACT Ravulizumab, a second‐generation complement component 5 inhibitor (C5i) derived from eculizumab, with improved pharmacokinetics, is the current standard‐of‐care treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), where available.
Alexander Röth, Christopher J. Patriquin, Jeff Szer, Louis Terriou, Ami S. Patel, Jesse Metzger, Philippe Gustovic, Jun‐ichi Nishimura, Robert A. Brodsky   +8 more
wiley   +1 more source

The Association of Sleeping Duration and Sleep Problems With All‐Cause Mortality Among a Cohort of Industrial Workers Followed Up for 36 Years

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Sleep duration is a well‐established factor associated with all‐cause mortality and cardiovascular mortality. Poor sleep quality was also suggested to affect all‐cause mortality risk among adults. The Cardiovascular Occupational Risk Factor determination in Israel Study (CORDIS) is a prospective cohort study of industrial workers ...
Gil Harari, Anat Gesser‐Edelsburg
wiley   +1 more source

Association between physical function parameters and fracture risk in older women in primary health care in southern Brazil. [PDF]

Arch Osteoporos
Dal Osto LC, Roland LF, Pinto MN, de Oliveira VP, Vianna KT, de Mello RGB, Spritzer PM, Fighera TM.   +7 more
europepmc   +1 more source

Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision‐Making and Polygenic Embryo Screening

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Polygenic risk scores (PRS) estimate individuals' genetic risk for developing multifactorial conditions. Recent genome‐wide association studies have enabled development of psychiatric PRS, which hold potential to streamline diagnosis and treatment of psychiatric conditions.
Lauren A. Ginn, Amanda R. Merner, Page M. Trotter, Kaitlynn P. Craig, Abigail C. Martinez, Ana Lucía Battaglino, Dorit Barlevy, Daphne M. Ayton, Takahiro Soda, Eric A. Storch, Gabriel Lázaro‐Muñoz, Stacey Pereira   +11 more
wiley   +1 more source