Results 91 to 100 of about 6,069,490 (350)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Lightweight bamboo structures - Report on 2021 International Collaboration on Bamboo Construction

Sustainable Structures, 2023
2021 International Collaboration on Bamboo Construction was held from September 1 to December 1, 2021. The practice was held by the College of Civil Engineering of Nanjing Forestry University, University College London, International Bamboo and Rattan ...
Assima Dauletbek, Xin Xue, Xinqi Shen, Haitao Li, Zixian Feng, Rodolfo Lorenzo, Kewei Liu, Edwin Zea Escamilla, Lianshu Yao, Xiaoyan Zheng   +9 more
doaj   +1 more source

Duality Symmetry in Momentum Frame [PDF]

, 2001
Siegel's action is generalized to the D=2(p+1) (p even) dimensional space-time. The investigation of self-duality of chiral p-forms is extended to the momentum frame, using Siegel's action of chiral bosons in two space-time dimensions and its ...
A. Maznytsia, A. Tseytlin, A. Tseytlin, B. McClain, D. Zwanziger, Dae Kil Park, Harald J. W. Müller-Kirsten, J.H. Schwarz, M. Henneaux, N. Marcus, P. Pasti, P. Pasti, P. Pasti, P.P. Srivastava, R. Banerjee, R. Floreanini, S. Deser, S. Deser, W. Siegel, Y.-G. Miao, Y.-G. Miao, Y.-G. Miao, Yan-Gang Miao   +22 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Fiber, microbiomes, and SCFAs: insights from companion animal models to inform personalized nutrition

mSystems
A recent study by A. Bhosle, M. I. Jackson, A. M. Walsh, E. A. Franzosa, et al. (mSystems 10:e00452-24, 2024, https://doi.org/10.1128/msystems.00452-24) enhances our understanding of dietary fiber’s impact on the gut microbiome and metabolome in ...
Leigh A. Frame
doaj   +1 more source

MULTIAGENT APPROACH FOR MANAGING THE INFORMATION SPACE OF CORPORATE SYSTEMS

Сучасний стан наукових досліджень та технологій в промисловості, 2018
The subject matter of the study is the integration and management of information resources of distributed computing corporate systems within the common information space.
Valentin Filatov, Valerii Semenets
doaj   +1 more source

Multi-frame Quality Enhancement for Compressed Video [PDF]

2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition, 2018
The past few years have witnessed great success in applying deep learning to enhance the quality of compressed image/video. The existing approaches mainly focus on enhancing the quality of a single frame, ignoring the similarity between consecutive ...
Ren Yang, Mai Xu, Zulin Wang, Tianyi Li
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Dialogue through film: engaging midwives, TBAs, and mothers to improve maternal health outcomes in Ghana’s Volta region

Frontiers in Global Women's Health
BackgroundMaternal mortality in Ghana remains high at 263 deaths per 100,000 live births, with the Volta Region showing particularly concerning figures; 37.2% of women give birth without a skilled provider. Many rely on Traditional Birth Attendants (TBAs)
Sandrina Koppitz, Obehi Oseyomon Iziduh, Sonja Liggett-Igelmund, Janet Michel   +3 more
doaj   +1 more source

De l'expression du point de vue à l'anticipation textuelle : le rôle de à première vue

Discours, 2010
We propose a semantic and pragmatic analysis of the french locution à première vue (lit. “at first sight”) when it indicates a point of view (in the sense of Nølke, 1994) and plays a role in textual structuration (Charolles, 1997).
Véronique Lenepveu
doaj   +1 more source