Results 81 to 90 of about 1,899,004 (298)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Supersnaps Clip Frame

open access: yes, 2010
Clip frame, glass frame with chipborad backing. Factory sealed with polystyrene casing. Marked 'Exclusive to Supersnaps'. Maker: Supersnaps. Date: 1992 (circa) - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Dangers of the chronic stress response in the context of the microbiota-gut-immune-brain axis and mental health: a narrative review

open access: yesFrontiers in Immunology
More than 20% of American adults live with a mental disorder, many of whom are treatment resistant or continue to experience symptoms. Other approaches are needed to improve mental health care, including prevention. The role of the microbiome has emerged
Alison Warren   +3 more
doaj   +1 more source

La Turquie : instrument de politisation, objet de politisation

open access: yesEuropean Journal of Turkish Studies, 2015
This paper analyses the politicization process in France of Turkey’s EU bid. In 2002 the President of the Convention on the future of Europe, V. Giscard d’Estaing, was one of the first leaders to take a strong political stand against Turkey’s EU bid. The
Claire Visier
doaj   +1 more source

Fusion frames and g-frames

open access: yesJournal of Mathematical Analysis and Applications, 2008
The authors study generalized, i.e., \(g\)-frames in a Hilbert space \(U\), that is, sequences \((\Lambda_i)_{i\in I}\) of linear operators \(\Lambda_i:U\to V_i\) such that \[ A\| f\| ^2 \leq \sum_{i\in I} \| \Lambda_i f\| ^2 \leq B \| f\| ^2, \] for some positive constants \(A\) and \(B\).
Khosravi, Amir, Musazadeh, Kamran
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

COGNITIVE SEMANTICS OF NOUNS IN DENUMERATIVE WORD FORMATION (BASED ON UKRAINIAN LANGUAGE) [PDF]

open access: yesAlfred Nobel University Journal of Philology
Revival of interest in the linguistic-cognitive interpretation of the deep level of language, as a means of facilitating the computerization of the semantic continuum of derived words, is driven by the schemati- zation of both implicit and explicit ...
Olha V. Kostryba
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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